Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands Repository

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Recent Submissions

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Association of Opium Usage with Blood Pressure and Fasting Blood Sugar Based on Fasa Adults Cohort Study Data
(Brieflands, 2025-01-13) Kimia Deris; Mojtaba Farjam; Saeideh Zareei; Maryam Kazemi
Background: There is a belief that opium consumption has a protective effect on hypertension and diabetes, which are important risk factors for cardiovascular disease. Objectives: This study aimed to compare blood pressure and blood sugar measurements between opium users and non-users. Methods: This cross-sectional study is based on the Fasa Adults Cohort Study (FACS). Participants from FACS who had no history of diabetes or hypertension with medication were included in this study. Systolic and diastolic blood pressure as well as fasting blood sugar (FBS) were compared between participants who use opium (regularly or ever) and those who do not, across different sociodemographic characteristics such as sex, marital status, employment, smoking, and other variables such as age, BMI, and physical activity. To control for the effect of confounders, a linear regression model was used in SPSS version 22. Results: A total of 7,428 adults participated in this study. The mean age of participants was 46.5 years. Of the participants, 27.05% were opium users. The mean diastolic blood pressure was 73.18 mmHg in non-opium users, while it was 70.95 mmHg in opium users (P = 0.000). The mean systolic blood pressure was 105.20 mmHg in opium users, compared to 107.78 mmHg in non-users (P = 0.000). The mean fasting blood sugar was 86.75 mg/dL in non-opium users and 85.88 mg/dL in opium users (P = 0.019). Lower blood pressure was observed in opium users despite higher fasting blood sugar levels. Conclusions: After controlling for confounders such as age, sex, smoking, BMI, physical activity, and calorie intake, both systolic and diastolic blood pressure were lower in opium users, while fasting blood sugar was higher. Given the numerous side effects of opium, it should not be used arbitrarily. However, these findings could be useful when making clinical decisions for diabetic or hypertensive individuals who are opium users.
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Exploring Skin Conditions: Medical and Herbal Approaches to Treatment
(Brieflands, 2024-12-31) Monika Nijhawan; Bhavana Jidige; Sneha Nawale; Rajeswari Aleti; Dedipya Goda Srivalli Vangala; Lakshmi Sowmya Talluri
Context: Skin diseases encompass a broad spectrum, ranging from common issues such as acne and dermatitis to more serious conditions like psoriasis, melanoma, and autoimmune disorders. These ailments can significantly affect both physical health and psychological well-being, often necessitating intricate and long-term management. Evidence Acquisition: Skin diseases arise due to a variety of factors, including genetic, environmental, and immunological influences, which can manifest as inflammation, infection, or abnormal cell growth. This review provides an in-depth examination of common skin diseases, their underlying causes, and current treatment approaches. Despite advancements in treatment, achieving long-term remission and managing side effects remain challenging, thereby highlighting the potential role of supportive herbal remedies, traditionally used for treating skin conditions. Results: Herbs such as Aloe vera, turmeric, neem, and chamomile are recognized for their anti-inflammatory, antimicrobial, and antioxidant properties, showing promise in the treatment of various skin disorders. Conclusions: This review explores the potential of these herbs, including their active compounds, and illustrates how herbal remedies might complement existing treatments, enhancing their effectiveness while minimizing side effects.
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COVID-19 Quarantine Fatigue in Adults with Congenital Heart Disease: The Predictive Role of Fear of COVID-19, Depression, and Anxiety
(Shiraz University of Medical Sciences, 2024-12-31) Nima Hajitabar; Amir Sam Kianimoghadam; Sama Jadidi; Fatemeh Karbalaei; Zahra Khajali; Mohammad Noori; Ali Vafaei; Boshra Shirzad; Asma Shahi
Background: The psychological consequences of the COVID-19 pandemic, such as fear of the virus, depression, anxiety, and quarantine fatigue, have become some of the most significant societal challenges of the 21st century due to the widespread nature of the disease. Objectives: This study aimed to examine the predictive roles of fear of COVID-19, symptoms of depression, and coronavirus-related anxiety in quarantine fatigue among patients with congenital heart disease. Methods: The research utilized a descriptive-correlational design. The statistical population comprised all patients with congenital heart disease referred to Shahid Rajaei hospitals and (X-Country) Heart Center. A total of 105 patients were selected using a convenience sampling method. Data collection tools included the Coronavirus Anxiety Scale (CAS), the COVID-19 Fear Scale, the Depression Scale (DS), and the Quarantine Fatigue Scale. Pearson's correlation and multiple regression analyses were employed to analyze the data. Results: The findings revealed significant correlations between fear of COVID-19 (r = 0.52), coronavirus anxiety (r = 0.46), and depression symptoms (r = 0.61) with quarantine fatigue in patients with congenital heart disease (P < 0.01). Conclusions: This study demonstrates that fear of COVID-19, depression, and coronavirus-related anxiety are significant predictors of quarantine fatigue. Interventions focused on addressing the psychological impacts of COVID-19—such as reducing depression, anxiety, and fear—can yield positive outcomes. Such programs can serve as preventative measures to help individuals manage the quarantine fatigue associated with the pandemic.
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Integrative Analysis of Non-coding RNAs and Hippo Signaling Pathway in Hepatocellular Carcinoma Using Bioinformatics and Experimental Approaches
(Brieflands, 2025-01-11) Farzin Mirzaei-Nasab; Mehrdad Hashemi; Yousef Seyedena; Nazanin Hosseinkhan; Ahmad Majd
Background: Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal malignancies globally. Non-coding RNAs (ncRNAs) are pivotal in regulating gene expression and cancer progression, yet their precise functions within HCC pathways remain elucidated. Objectives: To investigate the role of ncRNAs in regulating key genes involved in Hippo signaling and HCC pathways and to identify potential novel regulatory mechanisms in HCC progression. Methods: Gene expression data from the GEO database (GSE14520) were analyzed for expression changes of LEF1, MOB1A, PRKCB, and SMARCA2 in HCC. Physical interactions between selected ncRNAs (lnc-LRR1-1:1, lnc-LRR1-1:2, and hsa_circ_0001380) and target mRNAs were predicted, using the long non-coding RNA-target analysis resource (LncTAR) tool. miRNA analysis was performed to identify potential competing endogenous RNA (ceRNA) mechanisms. qPCR analysis in HCC cell lines was conducted for experimental validation. Results: Significant upregulation of LEF1 and downregulation of PRKCB were observed in HCC samples. The strongest predicted interactions were identified between lnc-LRR1-1:2 and MOB1A isoforms. miRNA analysis suggested that the studied ncRNAs could act as ceRNAs. qPCR analysis confirmed upregulation of hsa_circ_0001380 and slight downregulation of lnc-LRR1-1:1,2 in HCC cell lines. Conclusions: This study unveils a complex regulatory network, where ncRNAs can modulate the expression of key genes in HCC. The predicted interactions, particularly between lnc-LRR1-1:2 and MOB1A, and between hsa_circ_0001380 and hsa-miR-193b-3p suggest novel regulatory mechanisms in HCC progression. These findings provide new insights into the role of ncRNAs in HCC pathogenesis and identify potential avenues for future research and targeted therapies.
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Association of ABO Blood Groups and Rh Factor with Periodontal Disease Prevalence in a Population from Saravan, Iran
(Brieflands, 2025-01-31) Somaye Ansari Moghadam; Saeid Hoseinbor; Masoud Bamedi; Alireza Ranjbaran
Background: Periodontal diseases, including gingivitis and periodontitis, are prevalent inflammatory conditions that can result in tooth loss and systemic health complications. Genetic factors, such as blood group antigens and Rh factor, may influence susceptibility to these conditions. Objectives: This study aimed to examine the association between ABO blood groups, Rh factor, and the prevalence of periodontal diseases in individuals visiting the Blood Transfusion Organization in Saravan, Iran. Methods: This cross-sectional study included 368 participants (200 men and 168 women), aged 19 - 57 years, with equal representation across the ABO blood groups (A, B, AB, and O). Clinical assessments were performed to evaluate periodontal status, and blood samples were collected for ABO and Rh factor typing. Statistical analysis was conducted using chi-squared tests and logistic regression to assess the relationship between blood group, Rh status, and periodontal disease prevalence. A P-value of < 0.05 was considered statistically significant. Results: Among the participants, 54.3% (n = 200) had periodontal diseases. Individuals with blood group B showed the highest prevalence of periodontal diseases (18.75%), followed by group O (14.68%), group A (12.5%), and group AB (8.43%). Rh-positive individuals had a significantly higher prevalence (51.1%) compared to Rh-negative individuals (3.26%). Logistic regression analysis indicated significantly increased odds of periodontal diseases in individuals with blood group B (OR = 2.111, 95% CI: 1.126–3.958, P = 0.020) and Rh-positive status (OR = 5.559, 95% CI: 2.824 - 10.944, P < 0.001). Conclusions: Blood group B and Rh-positive status are significantly associated with a higher prevalence of periodontal diseases, highlighting the role of genetic factors in disease susceptibility. These findings underscore the importance of personalized preventive and therapeutic approaches in dental care, particularly for individuals at greater genetic risk. Further research is necessary to confirm these associations and explore the underlying mechanisms.