Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands Repository

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Recent Submissions

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Loss and Bereavement: In Children
(Brieflands, 2025-02-18) Kimiya Sabagh; Mohammad Hosein Abdollahi Nodeh; Mahin Naderifar
Context: Mourning following the death of a loved one is a natural and necessary process, but some people lack the skills and abilities to deal with the grief process, which can lead to many psychological problems. Bereaved children are a vulnerable population at risk of social and psychological harm. Objectives: The present study aimed to investigate the effects of grief on children and effective interventions to increase adaptation to it. Evidence Acquisition: The present study was a review-type design based on the review of the literature on loss and bereavement in children, reactions, and effective interventions. The literature search was conducted in PubMed, Scopus, and Web of Science databases, as well as in the Google Scholar search engine up to December 2024. Relevant keywords and their combinations used for the literature search were as follows: Loss, bereavement, children. Results: Supportive interventions in children's traumatic bereavement include cognitive behavioral therapy, developing coping skills, relaxing activities (yoga), and creative counseling techniques (expressing feelings or experiences through poems, drawings, singing, dancing, writing and drawing trauma narratives, epitaphs which are short texts performed in honor of a deceased person, holding a memorial service, holding a holiday program that focuses on helping the child cope with the grief during important family holidays). Conclusions: Childhood grief reactions are distinct from those in adults and are affected by developmental and contextual factors such as the age of the child and changes in caregiving environments. Empirically supported interventions can help young people to navigate the many grief-related challenges.
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Echeveria subrigida Leaf Extracts Standardized for Isorhamnetin-3-O-Glucoside Show Antidiabetic Effects via the PI3K/Akt Pathway in Rats
(Brieflands, 2025-02-28) Yudith Escobar-Zuñiga; Francisco Delgado-Vargas; José Angel López-Valenzuela; Jesús Ricardo Parra-Unda; José Geovanni Romero-Quintana; Guadalupe Loarca-Piña; Margarita del Socorro Dávila-Paredes; Karen Virginia Pineda-Hidalto; Gabriela López-Angulo
Background: Treatments for type 2 diabetes mellitus (DM2) are not universally effective, underscoring the need for new therapeutic alternatives. Extracts of Echeveria subrigida have demonstrated potent in vitro activities, such as antioxidant and α-glucosidase inhibitory effects, as well as in vivo activities, including hypoglycemic, antihyperglycemic, immunomodulatory, and adaptogenic effects. Objectives: The present study aimed to investigate the antidiabetic mechanisms of ethanolic (EEEs) and methanolic (MEEs) extracts of E. subrigida, standardized for isorhamnetin-3-O-glucoside (I3G), in streptozotocin (STZ)-induced diabetic rats. Methods: The E. subrigida extracts, EEEs and MEEs, were obtained by maceration and standardized for the content of I3G. The antidiabetic effect was evaluated using STZ-induced diabetic rats, which were randomly allocated to experimental groups (n = 6). Isorhamnetin (ISO) and metformin (MET) treatments served as positive controls. Parameters were measured at least in triplicate, and means were compared using the Fisher test (P < 0.05). The following evaluations were conducted: Levels of monocyte chemoattractant protein-1 (MCP-1), leptin, and inflammatory-related cytokines in serum; expression of proteins in the phosphatidylinositol 3-kinase (PI3K) and adenosine monophosphate-activated protein kinase (AMPK) pathways; transcriptional expression of peroxisome proliferator-activated receptor alpha (PPARα) and sterol regulatory element-binding protein 1c (SREBP-1c) in liver tissue; and histology of the liver and pancreas. Results: All treatments, except ISO, demonstrated antidiabetic effects, with glucose levels in MET (183.75 ± 61.89 mg/dL) and MEEs (168.00 ± 48.10 mg/dL) rats comparable to healthy control (HC) rats (109.25 ± 6.11 mg/dL). Leptin levels decreased in diabetic control (DC) rats (0.17 ± 0.07 ng/mL), while levels in the EEEs (0.65 ± 0.06 ng/mL) and MEEs (0.77 ± 0.09 ng/mL) groups were similar to those of the HC group (0.71 ± 0.19 ng/mL). The levels (pg/mL) of cytokines (IL-10, IL-6, IFN-γ, and IL-4) were elevated in DC rats (72.26 ± 12.91, 36.72 ± 2.91, 4.56 ± 0.63, and 16.34 ± 2.06, respectively), but were effectively reduced in rats treated with EEEs (29.64 ± 2.86, 9.85 ± 2.92, 1.11 ± 0.24, and 6.71 ± 1.15, respectively) and MEEs (26.65 ± 5.31, 7.30 ± 1.89, 1.25 ± 0.28, and 5.55 ± 0.43, respectively). Liver histology showed nearly normal structures, although pancreatic histology revealed hypertrophied Langerhans islets across all DM2 groups. The Akt activation and inactivation of AS160 by phosphorylation were detected in the livers of EEEs and MEEs rats without AMPK activation. Additionally, these groups expressed the SREBP-1c mRNA. Conclusions: The EEEs and MEEs exhibited antidiabetic activity via the PI3K/Akt pathway, suggesting E. subrigida as a potential preventive or therapeutic agent for type 2 diabetes.
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It Bothers Me to Remember My Pregnancy: Lived Experiences of Female Faculty Members at Type 3 University in Iran on Pregnancy and Childbirth: A Phenomenological Study
(Brieflands, 2025-02-15) Hamidreza Kolivand; Marzieh Beigom Bigdeli Shamloo; Hadis Ashrafizadeh; Neda Rashidi
Background: During pregnancy, women encounter various physical and mental challenges, with severity influenced by their physical condition, underlying health issues, socio-economic status, and available support systems. Objectives: This study aims to explore the lived experiences of faculty members during pregnancy. Methods: This interpretative phenomenological study was conducted using Max van Manen's phenomenological research methods. Data were collected through semi-structured, in-depth, face-to-face interviews. A total of 7 participants were selected through purposive sampling. The interviews began with the question, "How did you experience your pregnancy?" To ensure rich data, maximum diversity sampling was employed. Data collection and analysis occurred concurrently. This research was conducted in 2023 at Dezful University of Medical Sciences, focusing on medical faculty members. Results: The findings revealed that the lived experiences of female faculty members in medical sciences universities in Iran during motherhood encompassed seven themes: Sick and tired body, mental instability, modified role, support failure, wrong policies, spiritual strictness, and resistance against traditionalism. Conclusions: The research indicates that the lack of family-friendly programs results in numerous challenges for female faculty members, including the financial burden of having children, conflicts between motherhood and professional responsibilities, ineffective demographic policies, pressures from traditional societal norms, and inadequate support systems.
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Effect of Two Different Doses of Neostigmine on the Gastric Residual Volume and Aspiration in Critically Ill Patients Under Enteral Feeding; A Comparative Controlled Randomized Trial
(Brieflands, 2025-02-28) Sameh Hamdy Abdelhamid Seyam; Ibrahim Elabd Hassan; Abdallah Elabd Hassan; Mostafa Mohamad Elsayed
Background: Delayed gastric emptying increases the risk of patient morbidity in the ICU. Intensive care researchers have exerted considerable effort to measure and regulate gastric residual volumes (GRV) in ventilator-operated patients. Objectives: This study examines a cross-sectional, double-blind clinical trial designed to assess the effect of the addition of neostigmine to metoclopramide GRV in ICU patients and the risk of aspiration in those patients. Methods: Participants were categorized into three groups: Group I (n = 41) and group II (n = 43) received neostigmine 1 mg and 2 mg, respectively, and a control group (group III, n = 40) received 10 mL of normal saline. All participants received an intravenous administration of 10 mg of metoclopramide. The GRV was measured every 3 hours before enteral feeding. Aspiration through nasogastric (NG) or orogastric (OG) tubes was done before the next due bolus of feeding. The study did not receive any external funding support. The possessed data was interpreted using the PASS program, which set the alpha error at 5% and the power at 80%. Results: There was a significant variation among the three groups regarding the GRV. Metoclopramide used alone, did not profoundly alter the GRV at various time intervals. However, the administration of neostigmine resulted in a significant reduction in GRV at 3 and 6 hours post-injection. The GRV increased six hours post-injection, indicating that the drug combination resulted in a short-term effect. We did not observe any significant link between GRV and aspiration incidence, which happened even with low-volume aspirations. We used immunoassay to determine pepsin in the collected tracheal aspirations. Conclusions: Combining neostigmine and metoclopramide can effectively reduce GRV in ICU patients receiving enteral nutrition.
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Investigation the Effect of Reactive and Proactive Exercises on Balance Performance and Balance Confidence in Stroke Patients: A Randomized Clinical Trial
(Brieflands, 2025-02-28) Faezeh Koohestani Dehaghi; Majid Ghasemi; Parisa Emami Ardestani; Ehsan Ghasemi
Background: Stroke is the leading cause of disability in adults. The most prevalent disorder following a stroke is a balance disorder, and the primary goal of rehabilitation treatment in these patients is to improve balance. Objectives: This study aims to compare the effects of various balance therapy exercises on balance performance and balance confidence in individuals with stroke. Methods: In this double-blind clinical trial, 30 individuals with stroke were randomly assigned to one of three groups: Control, reactive, and proactive. Of these, 27 patients completed the study. Participants underwent 12 treatment sessions over four weeks. The control group received conventional exercises, the reactive group received conventional exercises plus reactive exercises, and the proactive group received conventional exercises plus proactive exercises. Balance performance was evaluated using the Mini-BESTest and the activities-specific balance confidence (ABC) questionnaire at three stages: Before treatment, after treatment, and during a two-month follow-up period. Data analysis was conducted using SPSS version 20. Results: Intra-group analysis indicated significant improvements in balance (F = 64.694; P < 0.001; ηp2 = 0.729) and balance confidence (F = 76.002; P < 0.001; ηp2 = 0.760). At the end of the treatment, the proactive group exhibited better balance performance compared to the reactive group, while the reactive group demonstrated higher balance confidence than the proactive group. However, these differences were not statistically significant (P > 0.05). Conclusions: Balance performance and balance confidence improved significantly in all three treatment groups. However, the differences between the groups were not statistically significant. This study concludes that exercise therapy is an integral component of rehabilitation treatment for stroke patients.