Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands Repository

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Recent Submissions

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Effectiveness of Facial Massage and Exercise in Alleviating Visual Fatigue: A Systematic Review
(Brieflands, 2024-11-05) Hongxiu Chen; Wichai Eungpinichpong; Tanapat Ratanapakorn; Beibei Wang
Background: With the widespread use of electronic devices, visual fatigue has become a prevalent issue in modern society. Non-pharmacological interventions, such as facial massage and exercise, have been proposed as effective methods for alleviating visual fatigue. However, the specific effects and mechanisms behind these interventions require further exploration. Objectives: This systematic review aims to evaluate the effectiveness of facial massage and exercise in reducing visual fatigue and to explore the underlying mechanisms of these interventions. Methods: A comprehensive search was conducted across multiple databases, including PubMed, Web of Science, Scopus, and the Cochrane Library. Randomized controlled trials and crossover experiments were included for both quantitative and qualitative analyses of relevant studies. Results: The findings suggest that both facial massage and exercise can reduce visual fatigue. Facial massage alleviates eye strain by stimulating the parasympathetic nervous system, reducing stress and anxiety, relaxing muscles, and improving blood circulation. Exercise alleviates visual fatigue through two mechanisms: (1) enhancing overall blood circulation, reducing stress, improving sleep quality, and overall health; (2) directly exercising eye muscles through eye yoga, which helps relieve visual fatigue. Conclusions: Preliminary research indicates that facial massage, full-body exercise, and eye yoga hold potential as non-pharmacological interventions for visual fatigue. Eye yoga has experimental support for its ability to strengthen eye muscles and improve focus. Massage stimulates parasympathetic activity and boosts blood circulation, while full-body exercise enhances systemic circulation to relieve eye fatigue. Future research should focus on investigating the mechanisms of these interventions in more detail and comparing the effects of various types, intensities, and durations to provide more precise clinical recommendations.
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The Relationship Between Job Stress and COVID-19-Induced Anxiety Among Healthcare Workers in Chaharmahal and Bakhtiari, Iran: A Cross-Sectional Study
(Brieflands, 2024-06-30) Fatemeh Rezaei; Ebrahim Aghaei Brojeni; Maryam Nasirian
Background: Previous research has shown that the COVID-19 pandemic has negatively impacted the mental health of individuals, particularly healthcare workers (HCWs), who are at the front line of the battle against COVID-19. Objectives: This study aimed to investigate the correlation between job stress and COVID-19-induced anxiety among HCWs. Methods: This cross-sectional study was performed in the Chaharmahal and Bakhtiari province of Iran in 2022. Data were collected using three questionnaires, including the Demographic Questionnaire, the Health and Safety Executives (HSE) Questionnaire, and the Corona Disease Anxiety Scale (CDAS). To evaluate the correlation between job stress and COVID-19-induced anxiety, we employed logistic regression using SPSS software (version 22), considering a significance level of 0.05. Results: This study found that HCWs in Chaharmahal and Bakhtiari province experienced moderate levels of job stress, and approximately half of them reported mild COVID-19-induced anxiety. In addition, COVID-19-induced anxiety was influenced by two other factors: history of COVID-19 (OR = 2.24, 95% CI = 1.18 - 6.40) and the history of death in the family due to COVID-19 (OR = 3.46, 95% CI = 1.23 - 9.70). Also, this study showed that job stress increases COVID-19-induced anxiety (OR = 3.80, 95% CI = 1.95 - 8.21). Conclusions: Job stress has a direct positive effect on COVID-19-induced anxiety. However, the strengthening of the relationship between job stress and COVID-19-induced anxiety may be due to the confounding role of the COVID-19 pandemic. In addition, we must teach HCWs how to manage stress and anxiety during pandemics like the COVID-19 pandemic.
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Curcumin-Etoposide Synergy: Unveiling the Molecular Mechanisms of Enhanced Apoptosis and Chemoresistance Attenuation in Breast Cancer
(Brieflands, 2024-12-31) Bahar Jaberian Asl; Reza Afarin; Mahdi Hatami; Amineh Dehghani Madiseh; Mohammadreza Roshanazadeh; Mojtaba Rashidi
Background: Combining natural compounds with chemotherapeutic agents has emerged as a promising approach for cancer treatment. Curcumin (Cur), a natural polyphenol, is known for its anti-cancer properties, including the ability to induce apoptosis and arrest cell cycle progression. Objectives: This study aimed to evaluate the effects of Cur and etoposide (ETO), both individually and in combination, on the induction of apoptosis in breast cancer (BC) cell lines. Methods: The impact of Cur and ETO on cell proliferation was assessed using MTT viability assays. Apoptosis induction by these drugs was evaluated through Annexin V flow cytometry and caspase-3 and caspase-9 activity assays. Quantitative real-time PCR was employed to measure Bax and Bcl-2 gene expression levels. Western blotting was conducted to determine protein levels of p53, p21, Bax, and Bcl-2. Results: A non-significant dose of ETO was selected based on MTT assay results and combined with 75 µM of Cur. Curcumin enhanced ETO’s pro-apoptotic effect by increasing caspase activities. The combination of Cur and ETO significantly reduced Bcl-2 gene expression while upregulating Bax expression. Furthermore, treatment with this combination elevated the protein levels of p53, p21, and Bax, compared to ETO or Cur alone, while significantly decreasing Bcl-2 protein levels. Conclusions: Cur has the potential to amplify ETO-induced apoptosis in BC cells. This combination may offer a promising therapeutic approach for BC.
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The COVID-19 Pandemic and the Resilience of the Pharmaceutical Supply Chain: Lessons from Past Experiences and Strategies for the Future
(Brieflands, 2024-12-31) Mohamad Ali Aivazi; Hamid Reza Rasekh; Mohammad Peikanpour; Farzad Peiravian; Sajjad Esmaeili; Leila Zarei
Background: The pharmaceutical supply chain (PSC) faced numerous challenges, particularly during the COVID-19 crisis. Due to the supply chain (SC) 's vulnerabilities, it requires enhanced capabilities to address these challenges. In Iran, specific economic and political issues have intensified the vulnerabilities of the PSC. Objectives: This study investigates the issues caused by the COVID-19 crisis in the PSC, identifies and characterizes these issues, and recommends appropriate courses of action to address future SC disruptions. Methods: This study is a qualitative-quantitative analysis conducted in Iran during the COVID-19 crisis. Qualitative thematic analysis was performed from July 2022 until May 2023. Semi-structured, in-depth, face-to-face interviews with 23 Iranian PSC specialists were conducted until saturation was reached. The qualitative phase was analyzed using MAXQDA 2021. The quantitative phase included a survey of 547 individuals working in pharmaceutical manufacturing in Iran, with the questionnaires analyzed using SPSS 26. Results: In the qualitative phase, the research identified two main themes: (1) vulnerabilities and (2) capabilities, along with 15 subthemes providing solutions to enhance the resilience of the PSC. In the quantitative phase, findings from 64 questionnaires highlighted major vulnerabilities and capabilities necessary to create a resilient SC. The median score for vulnerabilities was 5.12, while the median score for capabilities was 5.39. Conclusions: According to the questionnaire results, the quantitative findings indicate that capabilities received a higher score, suggesting that this sector of the PSC demonstrated better resilience against the pandemic. This study, with its contextual focus, mixed-method approach, comprehensive analysis of vulnerabilities and capabilities, and sector-specific insights, offers a novel contribution to the understanding of SC resilience within Iranian pharmaceutical manufacturing. It also has the potential to promote further research in other sectors of the PSC.
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The Effect of Fordyce Happiness Training on Life Expectancy and Quality of Life in Hemodialysis Patients: An Intervention Study in Yazd, Iran
(Brieflands, 2024-11-05) Bahareh Fallah; Najmeh Baghian; Akram Mehrabbeik; Mehdi Karimi Zarchi; Hossin Nazmiah; Majid Hajimaghsoudi; Mohammad Hossein Dehghani
Background: Dialysis patients frequently experience issues such as fear, reduced social activity, and hopelessness due to lifestyle changes and treatment requirements. Objectives: This study aimed to determine the effect of Fordyce happiness training on quality of life and life expectancy in hemodialysis patients. Methods: This quasi-experimental intervention study involved 48 hemodialysis patients who were referred to Shahid Rahnemoun Hospital in Yazd, Iran, and selected through simple random sampling. Data collection tools included the Quality-of-Life Questionnaire for Kidney Patients (KDQOL-36) and the Miller Life Examination Questionnaire. Patients participated in ten 60-minute training sessions, held twice weekly. Data were collected at baseline and one month after the intervention and analyzed using SPSS 21 software. Results: Following Fordyce's happiness training, levels of potassium (K), creatinine (Cr), and blood urea nitrogen (BUN) in patients significantly decreased. Before the intervention, the mean scores for quality of life and life expectancy in dialysis patients were 51.9 ±28.27 and 169.75 ±11.95, respectively, which increased to 64.66 ±27.17 and 179.95 ±9.37 after the intervention. Paired t-test results indicated that Fordyce happiness training had a statistically significant positive effect on patients' quality of life (P < 0.05) and life expectancy (P < 0.05). Conclusions: The Fordyce happiness training program can improve quality of life and life expectancy in dialysis patients. In other words, happiness training may serve as a preventive strategy against mental disorders such as depression, anxiety, and life dissatisfaction in dialysis patients.