Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands

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Recent Submissions

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Effects of Lactobacillus sporogenesis on Pediatric Cholestatic Liver Disease: A Randomized, Triple-Blind, Placebo-Controlled Trial
(Brieflands, 2025-05-07) Nasrin Motazedian; Amirali Mashhadiagha; Seyed Ali Moosavi; Seyed Mohsen Dehghani; Mehrab Sayadi; Ahmad Gholami; Negar Azarpira; Nasrin Motazedian [0000-0001-9534-4014]; Seyed Mohsen Dehghani [0000-0001-5930-0110]; Mehrab Sayadi [0000-0003-2575-790X]
Background: Recent studies have demonstrated the beneficial role of probiotics in liver disease in both children and adults, although only a limited number of studies have been conducted. This randomized, triple-blind, placebo‐controlled trial investigated the impact of Lactobacillus sporogenesis on children with cholestatic liver disease. Methods: Children with cholestatic liver disease and no prior use of probiotics were randomly divided into two groups. Fifteen drops of probiotics (L. sporogenesis) and placebo were administered daily to group A (intervention) and group B (placebo), respectively, for four weeks. Basic laboratory data and pediatric end-stage liver disease (PELD) scores were assessed at baseline and two weeks after completing the probiotic intervention. Results: Fifty-six children were enrolled and followed in group A (n = 28) and group B (n = 28), with biliary atresia and progressive familial intrahepatic cholestasis being the most common disease etiologies. No statistically significant difference was observed in PELD scores between the two groups before and after the intervention. However, PELD scores decreased in both groups following the intervention, with a significant reduction observed in group A (19.25 ± 9.20 vs. 15.27 ± 8.94) (P = 0.025). Albumin levels significantly decreased in group B (control) during follow-up, while prothrombin international normalized ratio (INR) levels significantly increased in both groups. Conclusions: A four-week trial of L. sporogenesis (probiotics) as a complementary nutritional support showed promising results. However, further studies with larger sample sizes are necessary to validate these findings.
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The Antidepressant Potential of Heracleum persicum Essential Oil in the Forced Swim Test in Mice: Involvement of Antioxidant and Monoaminergic Mechanisms
(Brieflands, 2025-12-31) Seyedeh Saba Arabi; Mohammad Taher Bahrami; Sajad Fakhri; Mahdieh Eftekhari; Saeid Abbasi-Maleki; Seyedeh Saba Arabi [0009-0003-2808-2044]; Mohammad Taher Bahrami [0000-0001-5216-2448]; Sajad Fakhri [0000-0001-8265-8284]; Mahdieh Eftekhari [0000-0003-2786-5111]; Saeid Abbasi-Maleki [0000-0002-1578-8414]
Background: Previous studies have highlighted the significant role of oxidative stress in depression. Conversely, Heracleum persicum has demonstrated notable antioxidant properties. However, no study has been conducted to explore the antidepressant effects of H. persicum essential oil (HPEO) and its mechanisms of action. Objectives: This study investigates the antidepressant potential of HPEO in a forced swim test (FST). Methods: In this study, mice (22 - 28 g) were administered HPEO (125 - 500 mg/kg, i.p.) one hour before performing the FST. Additionally, mouse serum levels of glutathione (GSH), catalase (CAT), and nitric oxide (NO) were measured. To assess the role of the monoaminergic system in the mechanism of action of the essential oil, various receptor antagonists were administered one hour before HPEO (500 mg/kg). Results: The HPEO (500 mg/kg) increased serum CAT and GSH levels and decreased NO levels. Acute administration of HPEO (250 and 500 mg/kg) reduced immobility in the FST without significantly altering the animals' locomotion in the open field test (OFT). Pretreatment of the mice with sulpiride, haloperidol, SCH23390, yohimbine, prazosin, p-chlorophenylalanine (pCPA), WAY100135, ketanserin, prazosin, and reserpine restrained the antidepressant potential of HPEO. Conclusions: For the first time, this research demonstrates the antidepressant potential of HPEO, which appears to be mediated by dopaminergic, serotonergic, and noradrenergic systems, as well as antioxidant mechanisms in the FST.
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Self-acceptance in Adolescent Girls: The Roles of Body Image and Perfectionism with Mental Toughness as a Mediator
(Brieflands, 2025-04-30) Eshagh Raisi Ahvan; Kobra Hajializadeh; Eghbal Zarei; Kobra Hajializadeh [0000-0002-8698-9790]
Background: Body image, perfectionism, and mental toughness can significantly influence self-acceptance in adolescent girls, affecting their psychological well-being. Objectives: This study investigated how body image and perfectionism influence self-acceptance in adolescent girls, with mental toughness as a mediating factor. Methods: This correlational study included 400 female high school students from Kahnuj during the 2023 - 2024 academic year. Data were collected using Cash's (2015) Body Image Questionnaire, Clough et al.'s (2012) Mental Toughness Questionnaire, Chamberlain and Haaga's (2021) Unconditional Self-acceptance Questionnaire, and Short et al.'s (2010) Perfectionism Questionnaire. Analysis employed Pearson correlation, multiple regression, and the Sobel test using SPSS 25 and Amos 24. Results: Mental toughness significantly mediated the relationships between self-acceptance and body image [variance accounted for (VAF) = 0.321] and positive perfectionism (VAF = 0.263), but not negative perfectionism (VAF = 0.126). In addition, significant direct effects were observed between body image and mental toughness (β = 0.26, P = 0.001), positive perfectionism and mental toughness (β = 0.23, P = 0.007), negative perfectionism and mental toughness (β = -0.24, P = 0.004), body image and self-acceptance (β = 0.17, P = 0.001), positive perfectionism and self-acceptance (β = 0.20, P = 0.001), negative perfectionism and self-acceptance (β = -0.52, P = 0.001), and mental toughness and self-acceptance (β = 0.31, P = 0.001). Model fit showed acceptable values: Chi-square/degrees of freedom = 4.26, Goodness-of-Fit Index = 0.90, Incremental Fit Index = 0.926, Comparative Fit Index = 0.926, root mean square error of approximation = 0.078. Conclusions: Positive body image and adaptive perfectionism enhance mental toughness, thereby fostering self-acceptance, whereas maladaptive perfectionism directly reduces self-acceptance. Interventions should target these factors to promote psychological well-being in adolescent girls.
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Artificial Intelligence in Managing Liver Cirrhosis and Variceal Bleeding: A Review
(Brieflands, 2025-12-31) Yueyu Shen; Yong Chen; Xiaohan Wang
Context: Liver cirrhosis (LC) represents a major driver of mortality on a global scale, with upper gastrointestinal (GI) bleeding (UGIB) considerably increasing its related mortality risk. The objective of this review is to investigate the applicability of artificial intelligence (AI) and machine learning (ML) in managing LC and its complications, particularly esophageal variceal bleeding (EVB). Evidence Acquisition: This study was performed by searching electronic databases and search engines from 2014 to December 2024, thereby including articles that examined the effects of AI on patients with LC bleeding. Results: This review synthesizes findings from multiple studies to highlight the limitations of current scoring systems and summarizes the latest progress of AI and ML in detecting esophageal/gastric varices (EV/GV), diagnosing liver fibrosis (LF) and LC, and predicting the prognosis and complications in patients with LC. Conclusions: Overall, AI and ML offer more precise and personalized decision support for managing LC. Future research should focus on optimizing models and conducting multi-center validations to ensure their clinical reliability and generalizability.
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Isometric or Isotonic Exercises in Alleviating Chronic Neck and Shoulder Pain and Enhancing Quality of Life Among Computer Users with Upper Crossed Syndrome: A Randomized Controlled Trial
(Brieflands, 2025-06-30) Arash Khaledi; Hooman Minoonejad; Arash Khaledi [0000-0001-8555-6267]; Hooman Minoonejad [0000-0002-5983-8102]
Background: Millions of computer users experience chronic neck and shoulder pain (CNSP) and reduced health-related quality of life (HRQoL) due to upper cross syndrome (UCS). While strengthening exercises for the posterior trunk alleviate symptoms, it remains unclear whether isometric or isotonic exercises are more effective. Objectives: This study aimed to compare the effects of isometric and isotonic exercises on CNSP and HRQoL in individuals with UCS, and to evaluate these outcomes against a non-intervention group. Methods: In this randomized clinical trial (RCT), 43 UCS patients with CNSP were divided into three groups: Isometric exercises (n = 15), isotonic exercises (n = 14), and a control group (n = 14). Over 8 weeks, exercise groups completed 3 sessions per week (40 - 60 minutes each). Pain was assessed using the Visual Analog Scale (VAS) and HRQoL was assessed using the 36-item short form health survey (SF-36) questionnaire, both pre- and post-intervention. Results: Both isometric and isotonic exercises significantly reduced CNSP and improved HRQoL compared to the control group. Isometric exercises yielded a 70.4% pain reduction (P < 0.001) and a 14.9% HRQoL improvement (P = 0.002), while isotonic training showed a 47.6% pain reduction (P = 0.001) and a 17.7% HRQoL improvement (P < 0.001). Between-group differences were not statistically significant (pain: P = 0.853; HRQoL: P = 0.999). Although isometric exercises slightly favored pain reduction and isotonic exercises showed marginal HRQoL gains, these differences should not be overstated. Conclusions: Both isometric and isotonic exercises improved CNSP and HRQoL in UCS patients, with no significant difference between them. Slight trends favoring each should be interpreted cautiously. Longer-term studies are warranted.