Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.


Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Recent Submissions

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Real and Perceived Motor Competence Are Further Developed Through the Integration of Modern Teaching Methods with Inclusive Education
(Brieflands, 2024-11-30) Behzad Mohammadi Orangi; Mehdi Shahbazi; Hadi Abbaszadeh Ghanati; Mehdi Shahbazi [0009-0001-3529-2491]
Background: Physical education training is the foundation and foundation for learning sports skills and everyday activities. The study aimed to compare the effects of different educational methods—linear pedagogy (LP), non-linear pedagogy (NLP), differential learning (DL), and teaching games for understanding (TGFU)—combined with inclusive education on the perceived and actual motor skills of children. Methods: Each group consisted of 12 typically developing children and 4 children with disorders [attention deficit hyperactivity disorder (ADHD) and developmental coordination disorder (DCD)], with a mean age of 10.22 ± 1.73 years. Futsal-based interventions were conducted over a two-month period. Data were analyzed using a 2 (experiment) × 4 (group) ANOVA test at a significance level of 0.05. Results: The results showed that the effect of group * time and time was significant (P < 0.05). LSD indicated a significant difference in motor skills between the LP and NLP, LP and DL, and LP and TGFU groups. However, no significant difference was observed between the DL and NLP, DL and TGFU, and NLP and TGFU groups. There was a significant difference in perceived motor competence between the LP and NLP, and LP and TGFU groups. However, between LP and DL, DL and NLP, DL and TGFU, and NLP and TGFU were not significant (P > 0.05). Conclusions: The results highlight the importance of incorporating non-linear training in physical education, where the environment and tasks are manipulated without direct instructions and feedback, within an inclusive environment.
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Lipid Profile Status and Cardiac Risk Factors in Opium Users Versus Non-users with Coronary Artery Disease: Insights from the National Persian Registry of Cardiovascular Disease (N-PROVE)
(Brieflands, 2025-03-31) Sima Sobhani Shahri; Marzieh Heshmati; Seyed Ali Moezi Bady; Nahid Azdaki; Saeede Khosravi Bizhaem; Fahimeh Nikraftar; Alireza Khosravi; Toba Kazemi; Seyed Ali Moezi Bady [0000-0002-9128-6424]; Nahid Azdaki [0000-0002-9496-9343]; Saeede Khosravi Bizhaem [0000-0002-6087-2922]; Fahimeh Nikraftar [0000-0001-5752-1198]; Alireza Khosravi [0000-0003-0736-2090]; Toba Kazemi [0000-0002-6204-4514]
Background: Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. Opium consumption is prevalent in certain populations and has various health implications, including potential effects on cardiovascular risk factors. Objectives: This study aims to analyze the differences in cardiac risk factors, lipid profiles, and new lipid indices between opium consumers and non-consumers among patients undergoing coronary angiography. Patients and Methods: This cross-sectional analytical study was conducted on patients who underwent coronary angiography at Razi Hospital in Birjand from March 2018 to March 2021. Participants included individuals with stenosis greater than 50% in at least one coronary artery. Patients were categorized into two groups: Opium consumers and non-consumers, based on self-reported usage during angiography. Data on demographics, medical history, Body Mass Index (BMI), and lipid profiles, including total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were extracted from patient records. New lipid indices were calculated using established formulas. All patients who underwent coronary angiography during this time frame were included in the study, ensuring a comprehensive sample. Descriptive statistics and comparative analyses were performed using SPSS software, version 22, considering a significance level of P ≤ 0.05. Results: Out of 1,888 patients with CAD, 24.5% were opium consumers. The mean age of opium users was lower than that of non-consumers (60.64 ± 11.14 years vs. 64.38 ± 11.38 years). A higher proportion were male (78.8% vs. 65.1%), and they had a lower BMI (24.67 ± 4.04 kg/m2 vs. 25.46 ± 4.77 kg/m2). The history of hypertension, diabetes mellitus (DM), and dyslipidemia was less prevalent in opium consumers. Additionally, triglyceride levels, Atherogenic Index, Triglyceride-Glucose (TyG) Index, and non-HDL cholesterol were significantly lower in the opium group compared to the non-consumers. However, the history of coronary angioplasty and smoking was greater among opium users. Conclusions: This study highlights the complex relationship between opium consumption and cardiovascular risk factors in coronary patients. Given the observed lower age and reduced risk factors among opium users, further research is warranted to confirm these findings and to investigate the potential role of opium as an independent risk factor for CAD. Understanding these dynamics is crucial for developing targeted prevention and treatment strategies in affected populations.
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Multimodal Regional Anesthesia Combining Spinal and Erector Spinae Plane Block for Spine Surgery in a High-Risk Patient with Systemic Sclerosis: A Case Report
(Brieflands, 2025-04-30) Alireza Shakeri; Jina Behjati; Alireza Shakeri [0000-0001-8095-7168]
Introduction: The erector spinae plane block (ESPB) is a novel regional anesthesia technique that is increasingly incorporated into multimodal analgesia as part of enhanced recovery after surgery (ERAS) pathways in various surgical procedures, including spine surgery. Case Presentation: We report the successful use of spinal anesthesia (SA), ESPB, and magnesium sulfate in a high-risk patient with systemic sclerosis and pulmonary fibrosis undergoing laminectomy. A multimodal approach was selected due to the patient’s underlying condition. This strategy minimized respiratory complications associated with general anesthesia while providing effective surgical anesthesia and postoperative pain control without opioid-related complications. Conclusions: Our case highlights the utility of ESPB, not only for postoperative pain management but also as a valuable adjunct to primary anesthesia, especially in high-risk patients.
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The Effects of Vitamin D Supplementation on Vertigo and Tinnitus in Patients with Meniere’s Disease: A Randomized Clinical Trial
(Brieflands, 2025-12-31) Ali Talebi; Nasrin Yazdani; Amir Kasaeian; Sepide Talebi; Niayesh Mohebbi; Niayesh Mohebbi [0000-0002-1420-7286]
Background: The present study aimed to evaluate the impact of vitamin D supplementation as an adjuvant therapy on tinnitus and vertigo in individuals diagnosed with Meniere’s disease. Methods: The study was conducted from November 2021 to October 2022 at Tehran University Hospital, Tehran, Iran. This clinical trial involved 60 individuals diagnosed with Meniere’s disease and vitamin D deficiency. Participants were randomly allocated to receive either vitamin D (50,000 IU weekly) or a placebo for eight weeks. The study assessed the frequency, intensity, and duration of vertigo attacks, as well as several measures of dizziness and tinnitus, both before and after the intervention. Results: No significant change was observed in the number of vertigo attacks (P = 0.85), the duration (P = 0.52), or the severity of vertigo (P = 0.33) in the vitamin D group compared to the placebo group at the end of the trial. Additionally, vitamin D supplementation did not significantly affect the results of various dizziness and tinnitus indices at the study’s conclusion (P > 0.05). As expected, serum levels of vitamin D were significantly higher in the intervention group compared to the placebo group at the trial's endpoint (P < 0.001). Conclusions: Vitamin D supplementation did not significantly affect vertigo and tinnitus in patients with Meniere’s disease. Further clinical trials with larger sample sizes and longer durations are recommended to confirm these findings.
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Acne Treatment Based on Cannabinoids: Efficacy and Legislation Perspectives
(Brieflands, 2025-03-31) Helena Pocay Araujo; Thais Giovanetti Esteves Santos; Flavia Sobreira Mendonca Goncalves; Priscila Alves Balista; Rodrigo Vieira Gonzaga; Michelli Ferrera Dario; Helena Pocay Araujo [0009-0007-5586-2563]; Thais Giovanetti Esteves Santos [0009-0001-8011-8396]; Flavia Sobreira Mendonca Goncalves [0009-0005-1383-4164]; Priscila Alves Balista [0000-0001-8670-4217]; Rodrigo Vieira Gonzaga [0000-0002-2815-1383]; Michelli Ferrera Dario [0000-0002-0050-4378]
Context: Acne is a prevalent inflammatory condition affecting individuals globally, particularly during adolescence, and has a significant psychosocial impact. Its pathogenesis involves sebaceous hypersecretion, follicular hyperkeratinization, and microbial dysbiosis, primarily associated with Cutibacterium acnes. Conventional acne treatments, including topical and systemic therapies, often cause adverse effects, highlighting the need for new, safer options. Cannabidiol (CBD), a non-psychoactive compound from Cannabis sativa, has emerged as a promising candidate due to its anti-inflammatory and antioxidant properties. This review discusses acne pathophysiology and examines CBD's therapeutic potential alongside global regulatory perspectives on its use in cosmetics. Evidence Acquisition: A literature search was conducted for articles on acne pathogenesis, endocannabinoid systems, and CBD's pharmacological effects. Results: Acne’s inflammatory nature is driven by androgen-induced sebum production, follicular hyperkeratinization, and microbial imbalance, mainly involving C. acnes. Androgens activate receptors in sebaceous glands, increasing sebum production and contributing to pore blockages and inflammatory responses. Although effective, conventional treatments such as retinoids and antibiotics often have undesirable side effects, driving interest in plant-based alternatives. The CBD shows potential as an acne treatment by modulating inflammation through CB2 receptor and TRPV1 channel activation, which directly helps reduce the inflammatory response that contributes to acne severity. It also reduces sebocyte proliferation, addressing the hyperkeratinization that leads to clogged pores, and inhibits cytokines like TNF-α, reducing the inflammatory processes that exacerbate acne lesions. The CBD also acts as an antioxidant, mitigating oxidative stress associated with acne-related inflammation. Furthermore, CBD’s lipophilic nature facilitates its accumulation in the stratum corneum, enabling prolonged skin interaction with minimal systemic absorption. A review of regulations reveals varying levels of acceptance for CBD in cosmetics, with North America and Europe allowing its use under specific guidelines, while restrictions remain stricter in other regions. Conclusions: The CBD represents a multi-targeted, safer alternative for acne management, addressing key mechanisms of acne pathogenesis, such as inflammation, sebocyte activity, and oxidative stress, without the adverse effects of conventional treatments. Further studies are necessary to validate these findings in clinical settings and establish standardized guidelines for the safe inclusion of CBD in skincare products.