Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands Repository

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Recent Submissions

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Assessment of the Seroprevalence of Varicella zoster Virus in Young Adults Aged 15 – 35 Years Old in Mashhad, Iran
(Brieflands, 2024-04-30) Mahdieh Khoshakhlagh; Samaneh Abolbashari; Alireza Pasdar; Mohammad Taghi Shakeri; Mojtaba Meshkat; Ahmad Ghasemifard; Amin Hooshyar Chechaklou; Soroush Yazdani; Ali Parvin; Navid Pousti; Nima Boojar; Aida Gholoobi; Zahra Meshkat
Background: Varicella zoster virus (VZV) is highly contagious and can lead to two distinct diseases. Initially, it causes chickenpox, a primary infection common among children worldwide, characterized by itchy, red blisters that cover the body. After this initial outbreak, the virus can lie dormant in nerve tissues and may reactivate later in life as herpes zoster, commonly known as shingles, which presents as a painful rash. While chickenpox is generally mild and resolves on its own, it can cause severe complications, especially in vulnerable groups such as immunocompromised individuals or adults. These complications can range from bacterial superinfections and pneumonia to encephalitis. In rare cases, it may lead to life-threatening conditions like necrotizing fasciitis or toxic shock syndrome, highlighting the potential severity of what is often considered a childhood illness. Objectives: One of the main risk factors for varicella-zoster infection is the absence of immunity. Individuals who have not been vaccinated against or previously infected with the VZV are at risk of contracting chickenpox when exposed. Additionally, close contact with infected individuals increases the likelihood of transmission. People with chronic conditions or those undergoing immunosuppressive therapy are particularly vulnerable to severe complications from varicella-zoster infections. Therefore, this study was conducted to assess the seroepidemiology of antibodies against varicella zoster in the young adult population in Mashhad. Methods: This cross-sectional study was conducted in 2018 on men and women aged 15 to 35 years in Mashhad, northeast Iran. Random cluster sampling was utilized. Individuals undergoing treatment for rare diseases were excluded from the study. The enzyme-linked immunoassay (ELISA) technique was employed to assess the presence of IgG antibodies against varicella zoster in 724 serum samples. Data analysis was performed using SPSS 20, and the significance level was set at 0.05. Results: Overall, among the 724 participants aged 15 - 35 years old in Mashhad, the frequency of anti-varicella IgG seropositivity was 85.9%. Our results indicated significant associations between age (P = 0.001) and occupational status (P = 0.02) with varicella-zoster seroprevalence. Conclusions: We observed a high frequency of anti-varicella zoster IgG seroprevalence among young adults in Mashhad. Infants, pregnant women, and individuals with weakened immune systems are more likely to develop severe forms of chickenpox or experience complications from shingles, including pneumonia and encephalitis. Given the severe health problems caused by the varicella virus and its high prevalence in Mashhad, we recommend incorporating the varicella vaccine into the public vaccination program. Additionally, further examination of the burden of herpes zoster, including its impact on quality of life and healthcare utilization, can guide interventions to mitigate the consequences of this condition.
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Eighth International Congress and Eighteenth Annual Congress of Clinical Oncology
(Brieflands, 2024-04-30) Yasha Makhdoumi; Ali Ghanbari Motlagh; Seyed Mohammad Hosseini
This article does not have an abstract.
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Weekly Afatinib in the Treatment of Advanced Non-small Cell Lung Cancer with Egfr-G719c Mutation Followed by Lobectomy: A Case Report
(Brieflands, 2024-12-31) Dung Xuan Ho; Long Thien Phan; Hung Manh Vuong; Kha Nguyen Dang
Introduction: Lung cancer stands as the leading cause of cancer-related deaths worldwide. Over the past three decades, the advent of tyrosine kinase inhibitors (TKIs) has marked a significant turning point in the treatment of non-small cell lung cancer (NSCLC) harboring EGFR mutations. Notably, high response rates have been notably observed in cases with exon 19 deletions (Del19) and Exon 21 substitution L858R mutations. Conversely, the G719X mutation on exon 18 is less prevalent, with variable sensitivity across different generations of TKIs. Afatinib, a second-generation inhibitor, gained FDA approval for the initial treatment of EGFR-mutant metastatic NSCLC in 2013, though its role remains incompletely understood within a multidisciplinary treatment framework, particularly in combination with surgery. However, the standard daily dose of 40mg Afatinib has demonstrated poor tolerability, often resulting in adverse events such as diarrhea and skin toxicity, leading to treatment discontinuation. A recent strategy involving a weekly dose of 280mg Afatinib has shown promising outcomes and a reduced risk of adverse events. Case Presentation: This case report highlights a 50 - year-old female diagnosed with stage IVa right lung adenocarcinoma metastasizing to the left lung (cT3N0M1a), revealing the rare EGFR-G719C (exon18) mutation. Following this diagnosis, the patient underwent open lobectomy. Nine months post-surgery, a treatment approach involving 280mg weekly Afatinib was initiated. Subsequently, the patient was closely monitored for 16 months with no signs of recurrence. Conclusions: EGFR G719C exhibits sensitivity to Afatinib, endorsing the use of Afatinib with fewer adverse events compared to the traditional daily dosage. Our case further advocates for collaborative strategies between medical oncologists and surgeons in the management of advanced-stage NSCLC.
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Antibiotic Susceptibility of Klebsiella pneumonia Isolates from Hospitalized Patients in Three Referral Medical Centers in Isfahan, Iran
(Brieflands, 2024-05-08) Sayed Nassereddin Mostafavi Esfahani; Soodabeh Rostami; Abtin Astaraki
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