Effect of Zirconium Dioxide Nanoparticles on Glutathione Peroxidase Enzyme in PC12 and N2a Cell Lines
| Author | Elham Asadpour | en |
| Author | Hamid Reza Sadeghnia | en |
| Author | Ahmad Ghorbani | en |
| Author | Mohammad Taher Boroushaki | en |
| Issued Date | 2014-10-31 | en |
| Abstract | Today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-ZrO2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. However, there are some reports implying that use of nano-ZrO2 is associated with cytotoxic effects like inhibiting the cell proliferation, DNA damage and apoptosis. In the present study, we examined whether nano-ZrO2 alters cell viability and glutathione peroxidase (GPx) activity in two neuronal cell lines. | en |
| DOI | https://doi.org/10.22037/ijpr.2014.1569 | en |
| Keyword | Zirconium dioxide nanoparticles; PC12 cell line; N2a cell line; Oxidative stress; Glutathione peroxidase enzyme | en |
| Publisher | Brieflands | en |
| Title | Effect of Zirconium Dioxide Nanoparticles on Glutathione Peroxidase Enzyme in PC12 and N2a Cell Lines | en |
| Type | Original Article | en |
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