Diagnostic Value of Carotid Artery Intima-media Thickness in Patients with Type 2 Diabetes and Its Correlation with HbA1c Levels
| Author | Hamid Dehdashti Sharokh | en |
| Author | Mehrnoosh Zakerkish | en |
| Author | Amir Hossein Sina | en |
| Author | Azadeh Saki | en |
| Author | Farzaneh Forouzan | en |
| Author | Aaraf Jenabi | en |
| Issued Date | 2021-04-30 | en |
| Abstract | Objectives: This study aimed to assess the role of carotid ultrasonography and measure the carotid artery intima-media thickness (CIMT) and its correlation with hemoglobin A1c (HbA1c) to observe cardiovascular disease (CVD) risks in patients with type 2 diabetes mellitus (T2DM). Methods: In this observational study, 205 consecutive patients with T2DM from Golestan Hospital, Ahvaz, Iran, were included. We performed HbA1c measurements using high-pressure liquid chromatography (HPLC) with a thermo-system. Carotid arteries ultrasonography was performed with an Aloka SSD 5500 apparatus with a 7.5 MHz transducer. The CIMT was measured in the supine position with a slight neck extension. Results: There was no statistically significant difference between the two study groups in the duration of diabetes with CIMT (P = 0.425), while the differences in creatinine, HbA1c, and urine albumin were statistically significant (P = 0.020, P = 0.041, and P = 0.016, respectively). There was no correlation between CIMT and age (r = 0.19, P = 0.792) and duration of diabetes (r = 0.125, P = 0.081). Furthermore, there was no remarkable association between CIMT and weight (r = 0.12, P = 0.881) and FBS ( r = 0.062, P = 0.405). There was also a non-significant negative correlation between HbA1c% and CIMT (r = -0.127, P = 0.127). Conclusions: Ultrasound measurement of CIMT is a safe and relatively cost-effective way of diagnosing atherosclerosis. Thus, the ultrasound's predictive value as a safe and non-invasive examination may alert the related field experts early enough to intervene to prevent major cardiovascular complications. | en |
| DOI | https://doi.org/10.5812/jjcdc.111308 | en |
| Keyword | Diabetes | en |
| Keyword | HbA1c | en |
| Keyword | Intima-media Thickness | en |
| Keyword | Ultrasound | en |
| Publisher | Brieflands | en |
| Title | Diagnostic Value of Carotid Artery Intima-media Thickness in Patients with Type 2 Diabetes and Its Correlation with HbA1c Levels | en |
| Type | Research Article | en |
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