SRL-Coated PAMAM Dendrimer Nano-Carrier for Targeted Gene Delivery to the Glioma Cells and Competitive Inhibition by Lactoferrin
Author | Amir zarebkohan | en |
Author | Farhood Najafi | en |
Author | Hamid Reza Moghimi | en |
Author | Mohammad Hemmati | en |
Author | Mohammad Reza Deevband | en |
Author | Bahram Kazemi | en |
Issued Date | 2016-10-31 | en |
Abstract | Glioma, as a primary tumor of central nervous system, is the main cause of death in patients with brain cancer. Therefore, development of an efficient strategy for treatment of glioma is worthy. The aim of the current study was to develop a SRL peptide-coated dendrimer as a novel dual gene delivery system for targeting the LRP receptor, an up-regulated gene in both BBB and glioma cells. | en |
DOI | https://doi.org/10.22037/ijpr.2016.1920 | en |
Keyword | SRL peptide | en |
Keyword | PAMAM dendrimer | en |
Keyword | Gene delivery | en |
Keyword | C6 glioma | en |
Keyword | Targeted delivery | en |
Keyword | Brain tumor | en |
Publisher | Brieflands | en |
Title | SRL-Coated PAMAM Dendrimer Nano-Carrier for Targeted Gene Delivery to the Glioma Cells and Competitive Inhibition by Lactoferrin | en |
Type | Original Article | en |
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