Preparation of SLN-containing Thermoresponsive In-situ Forming Gel as a Controlled Nanoparticle Delivery System and Investigating its Rheological, Thermal and Erosion Behavior

AuthorGolnar Dorrajen
AuthorHamid Reza Moghimien
Issued Date2015-04-30en
AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems as potential vehicles for prolonged release of SLNs.en
DOIhttps://doi.org/10.22037/ijpr.2015.1640en
KeywordSolid lipid nanoparticle (SLN)en
KeywordIn-situ forming gelen
KeywordControlled releaseen
KeywordRheologyen
KeywordErosion.en
PublisherBrieflandsen
TitlePreparation of SLN-containing Thermoresponsive In-situ Forming Gel as a Controlled Nanoparticle Delivery System and Investigating its Rheological, Thermal and Erosion Behavioren
TypeOriginal Articleen

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