The Relation of Gluten-Free Diet and Quality of Life in Children with Celiac Disease: A Cross-sectional Study
| Author | Fariba Shahraki-Sanavi | en |
| Author | Manijeh Khalili | en |
| Author | Sara Rezaei | en |
| Author | Alireza Khorram | en |
| Orcid | Fariba Shahraki-Sanavi [0000-0002-6937-0793] | en |
| Orcid | Manijeh Khalili [0000-0001-6754-5011] | en |
| Orcid | Sara Rezaei [0009-0007-6876-3222] | en |
| Orcid | Alireza Khorram [0000-0002-5790-7768] | en |
| Issued Date | 2025-08-31 | en |
| Abstract | Background: The present study aimed to determine the relationship between a gluten-free diet (GFD) and quality of life (QoL) in children with celiac disease (CD) and to evaluate the impact of additional factors that may affect both. Methods: This cross-sectional study was conducted in 2021 using a census sampling method. A total of 409 children aged ≤ 10 years with CD were recruited from referral clinics in Zahedan. Data were collected through a structured questionnaire. Statistical analyses were performed using independent t-tests, analysis of variance (ANOVA), chi-square tests, and Pearson’s correlation coefficient in SPSS version 23.0. Results: The gender distribution revealed a predominance of females (61.4%). The children had a mean age of 6.81 ± 2.46 years and a median disease duration of 3 years. The most common symptoms included abdominal pain (75.6%), weight loss (64.1%), and diarrhea (44.7%), while aggression (17.1%) and depression (11.5%) were the most frequently reported comorbidities. Poorer QoL was significantly associated with older age, longer disease duration, more comorbidities, and lower adherence to a GFD (all P < 0.01). Financial difficulties were also linked to reduced dietary adherence and worse QoL (P < 0.01). Conclusions: This study highlights that, while many children with CD maintain a relatively good QoL, several factors — particularly older age, longer disease duration, comorbid conditions, and financial hardship — negatively impact both dietary adherence and QoL. | en |
| DOI | https://doi.org/10.5812/healthscope-156761 | en |
| Keyword | Gluten-Free Diet | en |
| Keyword | Celiac Disease | en |
| Keyword | Diagnostic Test | en |
| Keyword | Quality of Life | en |
| Keyword | Symptom | en |
| Keyword | Comorbidity | en |
| Keyword | Financial Burden | en |
| Publisher | Brieflands | en |
| Title | The Relation of Gluten-Free Diet and Quality of Life in Children with Celiac Disease: A Cross-sectional Study | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- healthscope-14-3-156761-publish-pdf.pdf
- Size:
- 180.08 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF