Relationship Between Chronic Pain and Quality of Life in Patients With Acute Leukemia Undergoing Chemotherapy
| Author | Mojtaba Miladinia | en |
| Author | Shahram Baraz | en |
| Author | Abdolali Shariati | en |
| Author | Amal Saki Malehi | en |
| Author | Ahmad Amadzadeh | en |
| Orcid | Shahram Baraz [0000-0003-0113-7263] | en |
| Issued Date | 2015-07-01 | en |
| Abstract | Background: Chronic pain is one of the most prevalent symptoms in patients with acute leukemia and can affect patients' Quality of Life (QOL) that is a significant factor in assessment of cancer treatments. Also, the goal of curing hematological malignancies is to reach to increased survival and improvement of patients; and this goal will be fulfilled when QOL in patients is promoted. Objectives: The present study aimed to investigate the correlation between chronic pain and Health-Related QOL (HR-QOL) in patients with acute leukemia under chemotherapy in Ahvaz City, Iran. Patients and Methods: This descriptive-analytical study was performed on 90 patients (age range, 18 - 50 years) with acute leukemia under chemotherapy referred to Shafa Hospital in Ahvaz, Iran. The participants were selected through convenient sampling. The outcome measures included the Iranian version of the Short-Form 36 (SF-36) health survey, Numeric Rating Scale (NRS) for assessing the pain, and demographic questionnaire. Data analysis was performed using ANOVA, t-test, chi-square, with the significance level of 95%. Results: The average of pain severity was 6.03 ± 2.06, and the total average of HR-QOL was 46.83 ± 3.62, and the lowest average belonged to physical function (42.17 ± 25.75). No significant difference was found in the average pain between the two genders (P = 0.487); however, there was a statistically significant difference between HR-QOL and gender (P = 0.005). Moreover, no significant difference was detected between the average pain severity and acute leukemia type (P = 0.152). The findings also revealed a significant relationship between pain severity and aspects of HR-QOL, So that, all aspects of QOL were decreased with increased pain severity. Conclusions: The results of the study indicate that chronic pain and HR-QOL in patients with acute leukemia in Ahvaz are in a very adverse condition and require serious reform. The findings of the study can be helpful in the clinical decisions and health care programs to the therapeutic team. | en |
| DOI | https://doi.org/10.5812/jjcdc.27823v2 | en |
| URI | https://brieflands.com/journals/jjcdc/articles/21753 | en |
| Keyword | Leukemia | en |
| Keyword | Chronic Pain | en |
| Keyword | Quality of Life | en |
| Keyword | Chemotherapy | en |
| Publisher | Brieflands | en |
| Title | Relationship Between Chronic Pain and Quality of Life in Patients With Acute Leukemia Undergoing Chemotherapy | en |
| Type | Research Article | en |
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