Paraoxonase Inhibition by Propranolol

AuthorAlireza Jahangirien
AuthorMasoud Mahmoudianen
AuthorHassan Jalalizadehen
AuthorAbbas Shafieeen
Issued Date2004-07-31en
AbstractThere are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. Lineweaver-Burk and secondary plots were drawn and showed that propranolol is a mixed non-competitive inhibitor of paraoxonase.en
DOIhttps://doi.org/10.22037/ijpr.2010.593en
KeywordPropranololen
KeywordNon-selective beta-blockersen
KeywordParaoxonaseen
PublisherBrieflandsen
TitleParaoxonase Inhibition by Propranololen
TypeResearch Articleen

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