Comparison of Vitamin D Plasma Level in Women with or Without Endometriosis: A Case-Control Study
| Author | Shima Alizadeh | en |
| Author | Dorna Nasiri | en |
| Author | Fatemeh Keikha | en |
| Author | Farnaz Khatami | en |
| Author | Zahra Panahi | en |
| Author | Narges Zamani | en |
| Orcid | Fatemeh Keikha [0000-0003-1760-6394] | en |
| Orcid | Narges Zamani [0000-0001-9892-6183] | en |
| Issued Date | 2025-12-31 | en |
| Abstract | Background: Endometriosis is a debilitating gynecologic disease affecting millions of women worldwide. The potential role of vitamin D is of increasing interest. Previous studies have provoked controversy over vitamin D's role and have shown a correlation between endometriosis and low vitamin D serum levels. Objectives: This study assessed and compared vitamin D serum levels between women with and without endometriosis. Methods: We studied 47 patients with endometriosis who visited the Infertility and Reproductive Clinic at our tertiary hospital and compared their vitamin D levels with healthy control subjects (47 women). The analysis was performed using Mann-Whitney and chi-square tests. Results: The mean age of the women was 32.49, and the SD was 5.42. The Mann-Whitney test showed no significant relationship between the mean vitamin D levels and endometriosis diagnosis (P = 0.223). However, a significantly higher proportion of women with vitamin D deficiency (< 30 ng/mL) were diagnosed with endometriosis. This was confirmed by the chi-square test (odds ratio [OR] = 3.410; P = 0.008). Conclusions: In conclusion, while these results indicate an association between vitamin D deficiency and endometriosis, causality cannot be established based on this case-control study. Therefore, more studies are needed to determine the role of vitamin D in endometriosis. | en |
| DOI | https://doi.org/10.69107/fga-161198 | en |
| URI | https://brieflands.com/journals/fga/articles/161198 | en |
| Keyword | Deficiency | en |
| Keyword | Endometriosis | en |
| Keyword | Vitamin D | en |
| Publisher | Brieflands | en |
| Title | Comparison of Vitamin D Plasma Level in Women with or Without Endometriosis: A Case-Control Study | en |
| Type | Research Article | en |
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