Nitric Oxide is Necessary for Diazoxide Protection Against Ischemic Injury in Skeletal Muscle
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Abstract
Ischemia reperfusion injury (IR injury) is a common problem in clinical conditions. Researches have frequently revealed that ATP- sensitive potassium (KATP) channels and nitric oxide plays a role in protection against ischemic injury in skeletal muscle. The present study aimed at evaluating the possible link between this two pathways.