The Study of DNA Methylation of bax Gene Promoter in Breast and Colorectal Carcinoma Cell Lines
| Author | Mohsen Alipour | en |
| Author | Seyed Jalal Zargar | en |
| Author | Shahrokh Safarian | en |
| Author | Shamileh Fouladdel | en |
| Author | Ebrahim Azizi | en |
| Author | Naser Jafargholizadeh | en |
| Issued Date | 2013-06-30 | en |
| Abstract | Background: The Bcl-2 protein family members have known as essential controllers of mitochondrial pathway of apoptosis. Bax is a proapoptotic member of Bcl-2 protein family, which is well known to play crucial roles for apoptosis control. bax has been implicated as potential tumor suppressor in certain solid tumors such as breast and colorectal carcinoma. DNA methylation of promoter associated CpG islands has known as a common mechanism for gene inactivation in tumor cells. | en |
| DOI | https://doi.org/ | en |
| Keyword | CpG island | en |
| Keyword | DNA methylations | en |
| Keyword | Polymerase Chain Reaction (PCR) | en |
| Keyword | Breast cancer | en |
| Keyword | Colorectal cancer | en |
| Publisher | Brieflands | en |
| Title | The Study of DNA Methylation of bax Gene Promoter in Breast and Colorectal Carcinoma Cell Lines | en |
| Type | Research Article | en |
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