The Protective Effect of Melatonin on Diazepam-induced Genotoxicity in Peripheral Blood Lymphocytes Using Micronucleus Assay

Abstract

Background: Diazepam belongs to the benzodiazepine family of drugs and is mainly used for anxiety, muscle spasms, seizures, and insomnia. Long-term diazepam administration can cause genotoxicity, and oxidative stress is a likely molecular mechanism involved.