Runx3 Expression Inhibits Proliferation and Distinctly Alters mRNA Expression of Bax in AGS and A549 Cancer Cells
| Author | Maryam Torshabi |
| Author | Mohammad Ali Faramarzi |
| Author | Mojtaba Tabatabaei Yazdi |
| Author | Seyyed Naser Ostad |
| Author | Mohammad Hosein Gharemani |
| Issued Date | 2011-04-30 |
| Abstract | Runx3, a member of Runt-related transcription factor (Runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. In the present study, exogenous Run3 was transiently expressed in AGS (human gastric adenocarcinoma), with undetectable Runx3 protein and in A549 (human lung carcinoma) with low levels of endogenous Runx3 protein. |
| DOI | https://doi.org/10.22037/ijpr.2011.966 |
| Keyword | Runt |
| Keyword | Cancer cells |
| Keyword | Proliferation |
| Keyword | Cell death |
| Keyword | MRNA |
| Publisher | Brieflands |
| Title | Runx3 Expression Inhibits Proliferation and Distinctly Alters mRNA Expression of Bax in AGS and A549 Cancer Cells |
| Type | Original Article_imported |
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