Runx3 Expression Inhibits Proliferation and Distinctly Alters mRNA Expression of Bax in AGS and A549 Cancer Cells

AuthorMaryam Torshabien
AuthorMohammad Ali Faramarzien
AuthorMojtaba Tabatabaei Yazdien
AuthorSeyyed Naser Ostaden
AuthorMohammad Hosein Gharemanien
Issued Date2011-04-30en
AbstractRunx3, a member of Runt-related transcription factor (Runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. In the present study, exogenous Run3 was transiently expressed in AGS (human gastric adenocarcinoma), with undetectable Runx3 protein and in A549 (human lung carcinoma) with low levels of endogenous Runx3 protein.en
DOIhttps://doi.org/10.22037/ijpr.2011.966en
KeywordRunten
KeywordCancer cellsen
KeywordProliferationen
KeywordCell deathen
KeywordMRNAen
PublisherBrieflandsen
TitleRunx3 Expression Inhibits Proliferation and Distinctly Alters mRNA Expression of Bax in AGS and A549 Cancer Cellsen
TypeOriginal Articleen

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