In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
| Author | Baharak Khoshkholgh-Sima |
| Author | Soroush Sardari |
| Author | Jalal Izadi Mobarakeh |
| Author | Ramezan Ali Khavari-Nejad |
| Issued Date | 2015-01-31 |
| Abstract | Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of noncompliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need to develop novel antitubercular medicines that target new or more effective biochemical pathways to prevent drug resistant Mycobacterium. |
| DOI | https://doi.org/10.22037/ijpr.2015.1611 |
| Keyword | Mycobacterium |
| Keyword | Metabolic pathway |
| Keyword | Pantothenate synthetase (PanC) |
| Keyword | Antimycobacterial agents |
| Publisher | Brieflands |
| Title | In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery |
| Type | Original Article_imported |
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