<i>In-silico</i> Metabolome Target Analysis Towards <i>PanC</i>-based Antimycobacterial Agent Discovery

AuthorBaharak Khoshkholgh-Simaen
AuthorSoroush Sardarien
AuthorJalal Izadi Mobarakehen
AuthorRamezan Ali Khavari-Nejaden
Issued Date2015-01-31en
AbstractMycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of noncompliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need to develop novel antitubercular medicines that target new or more effective biochemical pathways to prevent drug resistant Mycobacterium.en
DOIhttps://doi.org/10.22037/ijpr.2015.1611en
Keyword<i>Mycobacterium</i>en
KeywordMetabolic pathwayen
KeywordPantothenate synthetase (<i>PanC</i>)en
KeywordAntimycobacterial agentsen
PublisherBrieflandsen
Title<i>In-silico</i> Metabolome Target Analysis Towards <i>PanC</i>-based Antimycobacterial Agent Discoveryen
TypeOriginal Articleen

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