Alteration of the K-Ras Gene Expression in Atypical and Nonatypical Hyperplastic Endometrium
Author | Narges Izadi-Mood | en |
Author | Soheila Sarmadi | en |
Author | Behzad Rostamnasl | en |
Issued Date | 2013-12-31 | en |
Abstract | Background: Endometrial cancer is the most common gynecologic malignancy that has often proceeded by a premalignant phase. Modern molecular and immunostaining methods for precancerous lesions diagnosis have been expanded. One of the genetic alternations in the endometrial cancer carcinogenesis is the mutational activation of the K-ras oncogene. K-ras mutation has recognized to occur at an early stage of neoplastic progression in the endometrium. The purpose of this study is to investigate the expression pattern of K-ras gene in atypical and nonatypical hyperplastic endometrium. | en |
DOI | https://doi.org/ | en |
Keyword | K-ras | en |
Keyword | Endometrial cancer | en |
Keyword | Endometrial hyperplasia | en |
Keyword | Immunohistochemistry | en |
Publisher | Brieflands | en |
Title | Alteration of the K-Ras Gene Expression in Atypical and Nonatypical Hyperplastic Endometrium | en |
Type | Research Article | en |
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