Alteration of the K-Ras Gene Expression in Atypical and Nonatypical Hyperplastic Endometrium

AuthorNarges Izadi-Mooden
AuthorSoheila Sarmadien
AuthorBehzad Rostamnaslen
Issued Date2013-12-31en
AbstractBackground: Endometrial cancer is the most common gynecologic malignancy that has often proceeded by a premalignant phase. Modern molecular and immunostaining methods for precancerous lesions diagnosis have been expanded. One of the genetic alternations in the endometrial cancer carcinogenesis is the mutational activation of the K-ras oncogene. K-ras mutation has recognized to occur at an early stage of neoplastic progression in the endometrium. The purpose of this study is to investigate the expression pattern of K-ras gene in atypical and nonatypical hyperplastic endometrium.en
DOIhttps://doi.org/en
KeywordK-rasen
KeywordEndometrial canceren
KeywordEndometrial hyperplasiaen
KeywordImmunohistochemistryen
PublisherBrieflandsen
TitleAlteration of the K-Ras Gene Expression in Atypical and Nonatypical Hyperplastic Endometriumen
TypeResearch Articleen

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