Synthesis and Cytotoxic Evaluation of Some Novel SulfonamideDerivativesAgainst a Few Human Cancer Cells
| Author | Mina Mirian | en |
| Author | Afshin Zarghi | en |
| Author | Sedighe Sadeghi | en |
| Author | Parisa Tabaraki | en |
| Author | Mojdeh Tavallaee | en |
| Author | Orkideh Dadrass | en |
| Author | Hojjat Sadeghi-aliabadi | en |
| Issued Date | 2011-10-31 | en |
| Abstract | Sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. In addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation in the G1 phase, disruption of microtubule assembly, suppression of the transcription activator Nf-Y, angiogenesis and matrix metalloproteinase (MMP). In recent years, novel synthesized sulfonamides have been introduced as antitumor, antiviral and anti-inflammatory agents. | en |
| DOI | https://doi.org/10.22037/ijpr.2011.980 | en |
| Keyword | Sulfonamides | en |
| Keyword | MTT assay | en |
| Keyword | MDA-MB-468 | en |
| Keyword | HeLa | en |
| Keyword | MCF-7 | en |
| Publisher | Brieflands | en |
| Title | Synthesis and Cytotoxic Evaluation of Some Novel SulfonamideDerivativesAgainst a Few Human Cancer Cells | en |
| Type | Original Article | en |
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