Could Cancer Initiate From Bone Marrow Progenitors?
| Author | Hmed Ben Nasr | en |
| Author | Serria Turky Hammami | en |
| Author | Khaled Zeghal | en |
| Issued Date | 2013-06-30 | en |
| Abstract | Background: Defining cancer stem cells and their origins is of much controversy, and constitutes a challenged knockout for cell targeting- anticancer drugs. Herein, we put forward a hypothetic model for cancer stem cells initiation from bone marrow stem cells. These later, will differentiate into an ancestral progenitor that activates a memorial program – the black box cassette- that is responsible of abnormal neo-organogenesis in the form of tumors and metastases. To approve this model, we assume that characterizing and investigating the most primitive forms of the bone marrow progenitors is required; both inside their niche and in circulation of cancer patients. | en |
| DOI | https://doi.org/ | en |
| Keyword | Bone marrow | en |
| Keyword | Progenitors | en |
| Keyword | Neoplasm | en |
| Keyword | Origin | en |
| Publisher | Brieflands | en |
| Title | Could Cancer Initiate From Bone Marrow Progenitors? | en |
| Type | Review Article | en |
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