The effect of zinc sulfate on immunologic response to recombinant hepatitis B vaccine in elderly

Abstract

Background: Hepatitis B is the major cause of chronic hepatitis and cirrhosis in Iran. Sanitation and immunization is one of the most effective measures for prevention of the disease which is now widely used in developing countries. However, the immune response to the vaccine varies by age.Objectives: To determine the effect of zinc sulfate on immune response to hepatitis-B vaccine in elderly.Patients and Methods: In a clinical trial on 140 subjects aged ≥40 years with a body mass index (BMI)