The Comparison of Cord Blood Omentin-1 Values of Newborns in the Different Birth Weights According to Gestational Age

Abstract

Objectives: Our aim in this study was to compare the values of omentin-1, which is an adipokine associated with postnatal metabolic complications, in the cord blood of newborns who were small for gestational age (SGA), appropriate for gestational age (AGA) and large for gestational age (LGA). Methods: This prospective, cross-sectional study was carried out with the measurement of omentin-1 values by Enzyme-Linked Immunosorbent method in the cord blood of the infants who were born at the delivery room of Ministry of Health, Istanbul Okmeydani Training and Research Hospital between 01/08/2016 and 31/01/2017. Results: In the study, omentin-1 values of 30 infants with AGA, 25 infants with LGA and 20 infants with SGA were measured and compared with each other. The mean of cord blood omentin-1 values in the newborn group with SGA was found to be significantly low compared to that of the newborns with AGA. However, no statistically significant difference was found between omentin-1 values of the three groups. Conclusions: We have determined serum omentin-1 levels to be lower in infants with SGA. Metabolic follow-up of infants with SGA is thought to be beneficial because low levels of omentin-1, which is an adipokine in metabolic functions in infants with SGA, may lead to the development of metabolic complications.