A Simple Approach for Diagnosis of Chronic Tuberculous Osteomyelitis: A Case Report

AuthorMohammadreza Salehien
AuthorSeyed Ali Dehghan Manshadien
AuthorZeynab Yassinen
AuthorMalihe Hassannejaden
OrcidMohammadreza Salehi [0000-0002-1987-5929]en
OrcidSeyed Ali Dehghan Manshadi [0000-0002-0619-2950]en
Issued Date2017-04-30en
AbstractIntroduction: Osteomyelitis is a secondary complication in 1% to 3% of patients with pulmonary tuberculosis (TB). Definite diagnosis of TB-associated osteomyelitis is challenging for clinicians, as biopsies of deep osteoarticular tissues are necessary. Case Presentation: We present the case of a 50-year-old man, admitted to Imam Khomeini hospital, Tehran, Iran in March 2014. According to his self-report, he had a chronic ulcer on his left foot since September 2012. In physical examinations, there was a painful sinus tract orifice (2 × 2 cm) on the left medial malleolus. Magnetic resonance imaging (MRI) of the foot revealed osteomyelitis in the left ankle. Two biopsies were taken from the wound edge, and Mycobacterium tuberculosis was detected via polymerase chain reaction (PCR) assay. Conclusions: Today, in the diagnosis of TB-associated osteomyelitis, it is a common practice to obtain 3 osteoarticular tissue biopsies for microbiological evaluation, PCR analysis, and histopathological assessment. We suspect that biopsies from the edge of the sinus tract orifice may help diagnose TB osteomyelitis.en
DOIhttps://doi.org/10.5812/archcid.57281en
KeywordTuberculosisen
KeywordOsteomyelitisen
KeywordPolymerase Chain Reactionen
PublisherBrieflandsen
TitleA Simple Approach for Diagnosis of Chronic Tuberculous Osteomyelitis: A Case Reporten
TypeCase Reporten

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