Association Between HTLV-1 Infection and Nasopharyngeal Carcinoma: A Case-Control Study
| Author | Mahmoudreza Kalantari | en |
| Author | Shakiba Kalantari | en |
| Author | Mohammad Reza Majidi | en |
| Author | Houshang Rafatpanah Baygi | en |
| Author | Sare Hosseini | en |
| Author | Seyed Alireza Javadinia | en |
| Orcid | Houshang Rafatpanah Baygi [0000-0002-1061-5864] | en |
| Orcid | Sare Hosseini [0000-0002-1242-763X] | en |
| Orcid | Seyed Alireza Javadinia [0000-0003-2467-837X] | en |
| Issued Date | 2021-12-31 | en |
| Abstract | Background: The northeast of Iran is one of the endemic regions of human T-cell lymphotropic virus type-1 (HTLV-1). This study aimed to evaluate the relationship between nasopharyngeal carcinoma and HTLV-1 infection in northeast Iran, an endemic area for HTLV-1. Methods: In this case-control study, paraffin-embedded nasopharyngeal tissue samples of patients with definitive nasopharyngeal carcinoma were evaluated for the presence of the HTLV-1 genome by polymerase chain reaction retrospectively. Results: Thirty patients with nasopharyngeal carcinoma and 30 healthy people were evaluated. All participants were matched in terms of age and gender, and all were living in Mashhad. The HTLV-1 genome was detected in only one of the people in the healthy group. Conclusions: The HTLV-1 infection and nasopharyngeal carcinoma did not correlate significantly. | en |
| DOI | https://doi.org/10.5812/rro-123953 | en |
| Keyword | HTLV-1 | en |
| Keyword | Nasopharyngeal Carcinoma | en |
| Keyword | Polymerase Chain Reaction | en |
| Publisher | Brieflands | en |
| Title | Association Between HTLV-1 Infection and Nasopharyngeal Carcinoma: A Case-Control Study | en |
| Type | Research Article | en |
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