Labdane-Type Diterpene and Two Flavones from <i>Salvia Sharifii</i> Rech. f. and Esfan. and their Biological Activities

AuthorMohammad Hossein Farjamen
AuthorAbdolhossein Rustaiyanen
AuthorElham Ezzatzadehen
AuthorAmir Reza Jassbien
Issued Date2013-04-30en
AbstractTwo flavones, ladanein and 6-hydroxy-5,7,4′-trimethoxyflavone and one labdane-type diterpene, ent-13-epi-manoyloxide, were isolated from an ethyl acetate-methanol extract of the aerial parts of Salvia sharifii. The compounds were purified using several chromatographic methods. Structural elucidation of the compounds was performed using their 1H and 13C-NMR data, EI mass and UV spectral data. The compounds have been subjected to antimicrobial, antioxidant and cytotoxic activity. The diterpene showed higher cytotoxic activity than the flavones while the later compounds were better antioxidants compared with the isolated diterpene.en
DOIhttps://doi.org/10.22037/ijpr.2013.1297en
KeywordTLadaneinen
Keyword6-hydroxy-5en
Keyword7en
Keyword4′-trimethoxyflavoneen
Keyword<i>Ent</i>-13-<i>epi</i>-manoyloxideen
KeywordAntioxidanten
KeywordAntimicrobialen
KeywordCytotoxicen
PublisherBrieflandsen
TitleLabdane-Type Diterpene and Two Flavones from <i>Salvia Sharifii</i> Rech. f. and Esfan. and their Biological Activitiesen
TypeOriginal Articleen

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