Voltammetric Determination of Cysteine (2-amino-3-mercaptopropanoic acid, CySH) by Means of 4,4′-biphenol as a Homogeneous Mediator
| Author | Mehrnoush Kamali | en |
| Author | Zeinab Pourghobadi | en |
| Issued Date | 2019-10-31 | en |
| Abstract | In the present research, 4,4′-biphenol was used as a homogeneous mediator for determining cysteine (CySH) on a Glassy Carbon Electrode (GCE). To describe the electrochemical properties of 4,4′-biphenol and to examine its electrocatalytic impacts on cysteine oxidation, both Cyclic Voltammetry (CV) and Linear Sweep Voltammetry (LSV) were employed. Our findings revealed that 4,4′-biphenol could significantly accelerate the reactions related to electron transfer to CySH. Moreover, the diffusion coefficient of CySH and its reaction with the catalytic constant of 4,4′-diphenoquinone was estimated via chronoamperometry technique. The results showed that cysteine concentration range of 10-1000 μM led to linear increases in the oxidation peaks, thus to providing a detection of 0.99 μM with R² = 0.993. A Relative Standard Deviation (RSD) of 2.5% was achieved after performing 7 cysteine replicates (100 μM), and CySH was successfully determined in real serum samples through the proposed approach. | en |
| DOI | https://doi.org/10.22037/ijpr.2019.1100829 | en |
| URI | https://brieflands.com/journals/ijpr/articles/124713 | en |
| Keyword | Cysteine | en |
| Keyword | 4 | en |
| Keyword | 4′-biphenol | en |
| Keyword | Homogeneous mediator | en |
| Keyword | Voltammetric determination | en |
| Publisher | Brieflands | en |
| Title | Voltammetric Determination of Cysteine (2-amino-3-mercaptopropanoic acid, CySH) by Means of 4,4′-biphenol as a Homogeneous Mediator | en |
| Type | Original Article | en |
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