Comparison of Tp-e Interval Between Obese and Healthy Children in Adolescence and its Correlation with Insulin Resistance in Obese Children
| Author | Dogan Cagri Tanriverdi | en |
| Author | Canan Yolcu | en |
| Author | Seniha Kiremitci Yilmaz | en |
| Author | Bagdagul Aksu | en |
| Author | Murat Elevli | en |
| Author | Kamil Sahin | en |
| Orcid | Bagdagul Aksu [0000-0003-3274-8024] | en |
| Orcid | Murat Elevli [0000-0002-0510-965X] | en |
| Orcid | Kamil Sahin [0000-0002-0443-2148] | en |
| Issued Date | 2022-06-30 | en |
| Abstract | Background: Prolonged cardiac repolarization may increase cardiovascular susceptibility to ventricular arrhythmias, leading to sudden cardiac death. This condition in obese children is not clearly demonstrated in childhood. Objectives: This study aimed to investigate the effect of obesity on cardiac electrical activity in children by comparing Tp-e intervals between obese and healthy children and evaluating the correlation between Tp-e intervals and insulin resistance in obese children. Methods: The study enrolled 50 obese and 50 healthy children. A pediatric cardiologist assessed electrocardiograms and echocardiographs. Electrocardiographic, demographic, and laboratory parameters were analyzed statistically. Results: There was no statistically significant difference between the two groups in age and gender (P > 0.05). The Tp-e intervals were statistically higher in the obese group than in the control group (P = 0.001). A statistically significant difference was found between the obese group with or without insulin resistance and the control group in Tp-e intervals (P = 0.001 for all). All other ECG parameters were similar in the patient and control groups. Conclusions: It is essential to recognize the early symptoms of future cardiovascular events in childhood obesity cases. Repolarization differences in obese children, when compared with the normal population, may reflect obesity-related early-stage subclinical findings. Prospective broad-based studies are needed to recognize these early changes. | en |
| DOI | https://doi.org/10.5812/ijp-115018 | en |
| Keyword | Children | en |
| Keyword | Obesity | en |
| Keyword | Repolarization | en |
| Keyword | Sudden Cardiac Death | en |
| Keyword | Tp-e Interval | en |
| Publisher | Brieflands | en |
| Title | Comparison of Tp-e Interval Between Obese and Healthy Children in Adolescence and its Correlation with Insulin Resistance in Obese Children | en |
| Type | Research Article | en |
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