The Use of Moxisaxin for Treatment of a Decompensated Cirrhosis Patient with Severe Pulmonary Infection
| Author | Junfei Jiang | en |
| Author | Jing Wang | en |
| Author | Zhiwen Yang | en |
| Issued Date | 2020-09-30 | en |
| Abstract | Introduction: Moxifloxacin is recommended for empirical antibiotic treatment of patients with cirrhosis. However, due to a lack of clinical safety data on moxifloxacin in Child-Pugh C patients, it is unknown how to use moxifloxacin in clinical practice. Case Presentation: A 76-year-old female with decompensated cirrhosis developed pneumonia during hospitalization. She had an initial failure to respond to imipenem/cilastatin + linezolid therapy. After three-day therapy with imipenem/cilastatin + moxisaxin, her infection symptoms rapidly improved. At this time, she presented a poor response with suspected hepatic encephalopathy. Given the worsening clinical symptoms caused by drug hepatotoxicity, moxisaxin was discontinued. Then, her body temperature rapidly raised. Conclusions: Moxisaxin may be a potentially useful antibiotic for hospital-acquired pneumonia in patients with decompensated cirrhosis, but further studies are needed to validate its hepatotoxicity. | en |
| DOI | https://doi.org/10.5812/jjm.103240 | en |
| Keyword | Decompensated Cirrhosis | en |
| Keyword | Hospital-Acquired Pneumonia | en |
| Keyword | Moxisaxin | en |
| Publisher | Brieflands | en |
| Title | The Use of Moxisaxin for Treatment of a Decompensated Cirrhosis Patient with Severe Pulmonary Infection | en |
| Type | Case Report | en |
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