Seroprevalence and Risk Factors for Hepatitis B in an Adult Population: The First Report from Birjand, South Khorasan, Iran
| Author | Masood Ziaee | en |
| Author | Azadeh Ebrahimzadeh | en |
| Author | Zohreh Azarkar | en |
| Author | Mohammad Hasan Namaei | en |
| Author | Amin Saburi | en |
| Author | Mohammad Fereidouni | en |
| Author | Bita Bijari | en |
| Author | Mehdi Karamian | en |
| Author | Gholamreza Sharifzadeh | en |
| Issued Date | 2016-09-01 | en |
| Abstract | Background: Infection with the hepatitis B virus (HBV) is an important global health problem. Knowledge of the geographic distribution pattern of HBV infection can help to control the spread of the disease. Objectives: To determine the prevalence of HBV infections and risk factors for the disease for the first time in Birjand, Southeastern Iran. Methods: This was an analytical cross-sectional study conducted in 2013 - 2014 of 5235 HBV cases in Birjand, South Khorasan Iran. Subjects aged 15 - 70 y were selected using the cluster sampling method. Blood samples were taken and tested at a reference laboratory for the hepatitis B core antibody (anti-HBc). Seropositive specimens were tested for the hepatitis B surface antigen (HBsAg). Results: The mean age (± SD) was 39.07 (± 14.04) y, and 786 (15%) subjects were anti-HBc positive. The prevalence of HBsAg was 1.6% (n = 85). The prevalence of anti-HBc seropositivity was significantly higher in subjects with a lower level of education (P = 0.09), older subjects (P = 0.001), intravenous (IV) drug users (P Conclusions: Although the frequency of HBsAg seropositivity in the present study was close to that observed in the overall Iranian population, the seroprevalence of anti-HBc was higher, possibly due to the exposure of the elderly to more risk factors. The risk factors were similar. These included a history of blood transfusions, cupping, hospital admission, endoscopy, or familial HBV/HCV infection, in addition to piercings and drug abuse. | en |
| DOI | https://doi.org/10.5812/hepatmon.36452 | en |
| Keyword | Hepatitis B | en |
| Keyword | Epidemiology | en |
| Keyword | Risk Factor | en |
| Keyword | Iran | en |
| Keyword | Hepatitis B Surface Antigen | en |
| Publisher | Brieflands | en |
| Title | Seroprevalence and Risk Factors for Hepatitis B in an Adult Population: The First Report from Birjand, South Khorasan, Iran | en |
| Type | Research Article | en |
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