Brain Metastases in a 12-Year-Old Girl with Osteosarcoma: A Case Report

Abstract

Introduction: Osteosarcoma accounts for about 3% of childhood cancers and this tumor is the most common primary bone tumor. Lung and bones are the most common sites of metastases. Brain metastases are very rare and account for approximately 1.8% to 5.6% of all metastases. Case Presentation: In this study, we reported osteosarcoma in a 12-year-old girl with primary lung metastases and subsequent brain metastases. Conclusions: In patients with osteosarcoma and evidence of pulmonary metastasis, performing brain imaging, even without evidence of neurologic sign and symptoms is reasonable.