Edaravone Decreases Paraquat Toxicity in A549 Cells and Lung Isolated Mitochondria
| Author | Mohammad Shokrzadeh | en |
| Author | Fatemeh Shaki | en |
| Author | Ebrahim Mohammadi | en |
| Author | Neda Rezagholizadeh | en |
| Author | Fatemeh Ebrahimi | en |
| Issued Date | 2014-04-30 | en |
| Abstract | Edaravone, an antioxidant and radical scavenger, showed protective effects against oxidative stress-like condition. Paraquat (PQ) is toxic herbicide considerable evidence suggests that oxidative stress and mitochondrial dysfunction contribute to PQ toxicity. In this study, protective effect of edaravone against PQ induced toxicity and reactive oxygen species (ROS) generation in A549 cells and lung isolated mitochondria were evaluated. | en |
| DOI | https://doi.org/10.22037/ijpr.2014.1514 | en |
| URI | https://brieflands.com/journals/ijpr/articles/125516 | en |
| Keyword | Edaravone | en |
| Keyword | Paraquat | en |
| Keyword | Oxidative stress | en |
| Keyword | Lung mitochondria | en |
| Keyword | A549 cells | en |
| Publisher | Brieflands | en |
| Title | Edaravone Decreases Paraquat Toxicity in A549 Cells and Lung Isolated Mitochondria | en |
| Type | Original Article | en |