Second-year Outcomes of Implementing Antimicrobial Stewardship Program in a Tertiary Pediatric Hospital
| Author | Iman Khorshidi-Malahmadi | en |
| Author | Setareh Sima | en |
| Author | Najmeh Ansari | en |
| Author | Azadeh Moghaddas | en |
| Orcid | Azadeh Moghaddas [0000-0003-0412-6172] | en |
| Issued Date | 2021-08-31 | en |
| Abstract | Background: The increasing use of antimicrobial agents and resistance is becoming a serious problem in pediatric patients. Hence, antimicrobial stewardship program (ASP) is implemented to lessen the consequences. Objectives: This report aimed to demonstrate the impact of ASP on antimicrobials utilization in a referral and tertiary pediatric hospital in Isfahan, Iran. Methods: We launched an ASP for inpatients in March 2018 at the Imam Hussain Hospital, which is a 186-bed pediatrics hospital. Data was collected by ASP multidisciplinary team and using hospital records during February 2017-January 2018 (pre-intervention) and February 2019-January 2020 (post-intervention) periods. Consumption data were expressed as defined daily doses (DDDs) per 100 patient-days (PD). Independent sample t-test and paired t-test were used to assess the significance of differences. The rates of antimicrobials resistance for the most common hospital pathogens were also tracked. Results: Utilization of total antimicrobials decreased meaningfully by 12.41% (from 62.11 DDDs/100 PD in February 2017-January 2018 to 54.40 DDDs/100 PD in February 2019-January 2020; P = 0.024). The results showed that the reduction in non-restricted antimicrobials was less (5.43%) than restricted antimicrobials (27.6%). Conclusions: According to our results, the use of antimicrobials, especially the broad-spectrum ones, and the health burden costs significantly decreased after implementing ASP. Thus, continuous monitoring and educational programs are recommended to reduce the negative effects of using antimicrobials. | en |
| DOI | https://doi.org/10.5812/jjm.118460 | en |
| URI | https://brieflands.com/journals/jjm/articles/118460 | en |
| Keyword | Antibiotic Stewardship | en |
| Keyword | Inpatients | en |
| Keyword | Pediatrics | en |
| Keyword | Broad-Spectrum Antibiotic | en |
| Publisher | Brieflands | en |
| Title | Second-year Outcomes of Implementing Antimicrobial Stewardship Program in a Tertiary Pediatric Hospital | en |
| Type | Research Article | en |
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