Changes in Thyroid Functional Tests in Breast Cancer Patients under Tamoxifen Therapy

Abstract

Background: Tamoxifen, a synthetic anti-estrogen agent, is administered as an adjuvant treatment in breast cancer. Since various studies have indicated that Tamoxifen can change some hormones and bound globolines, controversial results have been achieved using this medicine on Thyroid Functional Tests (TFT). The present study was conducted to investigate the effects of Tamoxifen on TFT in women with breast cancer referred to oncology clinic in Imam Hossein hospital between 2001 and 2002.