Anticancer Activity of Nanoparticles Based on PLGA and its Co-polymer: <i>In-vitro</i> Evaluation

Abstract

Attempts have been made to prepare nanoparticles based on poly(lactic-co-glycolic acid) (PLGA) and doxorubicin. Biological evaluation and physio-chemical characterizations were performed to elucidate the effects of initial drug loading and polymer composition on nanoparticle properties and its antitumor activity.