Formulation and Evaluation of <i>In-vitro</i> Characterization of Gastic-Mucoadhesive Microparticles/Discs Containing Metformin Hydrochloride

Abstract

The present study involves preparation and evaluation of gastric-mucoadhesive microparticles with Metformin Hydrochloride as model drug for prolongation of gastric residence time. The microparticles were prepared by the emulsification solvent evaporation technique using polymers of Carbomer 934p (CP) and Ethylcellulose (EC).