Does Retrograde Administration of Cardioplegic Solution Improve the Clinical Outcomes in Primary Coronary Artery Bypass Grafting?

Abstract

The quality of myocardial protection during Coronary Artery Bypass Grafting (CABG) has a direct effect on post-operative cardiac function, recovery and complications. The optimal route for delivery of cardioplegia is still in debate in patients with ischemic heart disease. This prospective randomized clinical study was designed to assess and compare the use of combined antegrade-retrograde cardioplegia versus antegrade cardioplegia in providing adequate myocardial preservation during coronary artery bypass graft surgery