Characterization and Evaluation of Novel Film Forming Polymer for Drug Delivery
| Author | Artish Mundada | en |
| Author | Prashant Satturwar | en |
| Author | Suniket Fulzele | en |
| Author | Sudhir Joshi | en |
| Author | Avinash Dorle | en |
| Issued Date | 2011-01-31 | en |
| Abstract | DB is a whitish to yellowish resin, characterized initially in terms of solubility, acid value, molecular weight (Mw), polydispersity index (Mw/Mn) and glass transition temperature (Tg). Neat plasticized films of DB (Damar Batu) are investigated for mechanical, water vapor transmission and moisture absorption properties. To improve the mechanical properties of the free films dibutyl sebacate, a hydrophobic plasticizer was added to film composition. The biomaterial was further investigated for sustaining the drug release from spherical units (multiparticulates). The core of pellet was prepared using Diclofenac sodium (10% w/w) as a model drug by extrusion and speronization. The drug containing pellets were coated using DB plasticized film-coating solutions. | en |
| DOI | https://doi.org/10.22037/ijpr.2010.879 | en |
| Keyword | Damar Batu | en |
| Keyword | Pellets | en |
| Keyword | Sustained release | en |
| Keyword | Films | en |
| Keyword | Protective coating | en |
| Publisher | Brieflands | en |
| Title | Characterization and Evaluation of Novel Film Forming Polymer for Drug Delivery | en |
| Type | Original Article | en |
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