A Comparison of Hepatocyte Cytotoxic Mechanisms for Docetaxel and PLGA-Docetaxel Nanoparticls
| Author | Bahram Daraei | en |
| Author | Marjan Aghvami | en |
| Author | Jalal Pourahmad | en |
| Author | Rassoul Dinarvand | en |
| Issued Date | 2017-01-31 | en |
| Abstract | Docetaxel (DTX) is one of the most widely used drugs in oncology due to its high efficacy against several cancers. Though, its routine clinical administration, formulated in tween 80, causes serious side effects. Polylactide-co-glycolide (PLGA), biodegradable polyester synthesized and approved for human use, is employed to overcome these problems. | en |
| DOI | https://doi.org/10.22037/ijpr.2017.2005 | en |
| Keyword | Docetaxel | en |
| Keyword | Polylactide-co-glycolide | en |
| Keyword | PLGA-DTX nanoparticles | en |
| Keyword | Cytotoxicity | en |
| Keyword | Rat Hepatocyte | en |
| Keyword | Silymarin | en |
| Publisher | Brieflands | en |
| Title | A Comparison of Hepatocyte Cytotoxic Mechanisms for Docetaxel and PLGA-Docetaxel Nanoparticls | en |
| Type | Original Article | en |