Clinical Characteristics of Chronic Hepatitis B Virus Infection in Immigrants from Sub-Saharan Africa
| Author | Hatef Massoumi | en |
| Author | Kathleen Buchheit | en |
| Author | Srinivas Gunturu | en |
| Author | Ju-En Thlick | en |
| Author | Paul Gaglio | en |
| Issued Date | 2017-04-30 | en |
| Abstract | Chronic hepatitis B virus (HBV) infection is a significant, worldwide burden due to it’s high prevalence, and risk of complications, including cirrhosis and hepatocellular carcinoma (HCC). Current literature suggests that African patients with chronic hepatitis B are at higher risk for hepatocellular carcinoma. The exact mechanism for the explanation for this observation is contentious and may be due to higher rates of chronicity, and/or exposure to hepatotoxins including aflatoxin. We sought to report the clinical characteristics of African born immigrants with chronic hepatitis B referred to a liver clinic in New York City. A total of 111 patients were enrolled. 19 patients (17%) had cirrhosis, and 14 patients (13%) had HCC at initial presentation. During the course of follow up, 13 patients (12%) died of complications of HBV, all of them related to HCC. Our case series revealed that a significant proportion of these patients manifested advanced complications of HBV such as cirrhosis or HCC. | en |
| DOI | https://doi.org/10.5812/hepatmon.41781 | en |
| URI | https://brieflands.com/journals/hepatmon/articles/12305 | en |
| Keyword | Hepatitis B | en |
| Keyword | Hepatoma | en |
| Keyword | Genotype E | en |
| Keyword | Sub-Saharan Africans | en |
| Publisher | Brieflands | en |
| Title | Clinical Characteristics of Chronic Hepatitis B Virus Infection in Immigrants from Sub-Saharan Africa | en |
| Type | Brief Report | en |
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