Association Between SARS-CoV-2 Infection and Cardiovascular Disease in Children and Adolescents: A Cross-sectional Study
| Author | Nagwa Mohamed Sabry Mahmoud | en |
| Author | Mostafa Ahmed El Sayed Ahmed Abu Elela | en |
| Author | Marwa Ghallab Abdelghany | en |
| Author | Moustafa Mohamad Abdel Raheem | en |
| Orcid | Nagwa Mohamed Sabry Mahmoud [0000-0002-2221-710X] | en |
| Issued Date | 2024-08-31 | en |
| Abstract | Background: The 2019 global coronavirus pandemic is triggered by severe acute respiratory syndrome due to corona virus 2 (SARS-CoV-2). This infection can cause myocardial damage, arrhythmias, acute coronary syndrome, and venous thromboembolism. Objectives: The objective of this study is to provide a comprehensive description of the cardiac manifestations observed in children who have been admitted to the pediatric intensive care unit as a result of SARS-CoV-2 infection. Methods: The current prospective cross-sectional study included patients from Minia University Hospital's pediatric intensive care unit (PICU) isolation unit from April 2022 to April 2023. The study comprised 80 patients divided into two groups: Group I included 46 Corona Virus Induced Disease (COVID-19)-positive patients with cardiac complications. Group II consisted of 34 patients with COVID-19 infection but without cardiac complications. Results: The frequency of cardiac complications was 41.3% (33 children) with arrhythmias and 9% (3 children) with SVT by electrocardiography (ECG), whereas 31.3% of children had myocardial dysfunction (EF < 50%, FS < 25%) on echocardiography (ECHO). In comparison, 7.5% had bundle branch block (BBB). Conversely, 1.3% had pancarditis, and 3.8% had first-degree A-V block. Conclusions: More data is needed on COVID-19's cardiovascular effects on children. We found that acute COVID-19 hospitalized children should have cardiac exams and cardiovascular monitoring. COVID-19 infection in children often impairs systolic function, and arrhythmia may arise in COVID-19 individuals. | en |
| DOI | https://doi.org/10.5812/jcp-140501 | en |
| Keyword | COVID-19 | en |
| Keyword | Pediatric | en |
| Keyword | Post-acute Sequelae of SARS-CoV-2 Infection | en |
| Keyword | Cardiac | en |
| Keyword | Myocarditis | en |
| Keyword | Dysrhythmia | en |
| Publisher | Brieflands | en |
| Title | Association Between SARS-CoV-2 Infection and Cardiovascular Disease in Children and Adolescents: A Cross-sectional Study | en |
| Type | Research Article | en |
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