Enhancement of Antinociceptive Effect by Co-administration of Amitriptyline and <i>Crocus Sativus</i> in a Rat Model of Neuropathic Pain

Abstract

The aim of this study was to evaluate the anti-nociceptive effects of a low, sub-effective dose of amitriptyline, in combination with the different doses of ethanolic and aqueous extracts of Crocus sativus following sciatic nerve chronic constriction injury (CCI) in rats.