Seroepidemiology of Infection with Herpes Simplex Virus Types 1 and 2 (HSV1 and HSV2) Among Asymptomatic University Students Attending Islamic Azad University of Kazeroun, Southwest of Iran

AuthorDaryoush Tayyebien
AuthorSfandiar Sharifien
Issued Date2010-04-30en
AbstractBackground: Herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) are common infectious agents worldwide. Data on prevalence of HSV-1 and HSV-2 infections are limited in Asia, especially in Iran. Our study aimed on determination of seroepidemiology of HSV-1 and HSV-2 infections in asymptomatic healthy students of Islamic Azad University of Kazeroun, Fars province, southwest of Iran. Patients and Methods: The study population included 360 students with a mean age of 22.2 years. Demographic data were gathered by a well-designed questionnaire. For serological studies, 5 ml of blood sample was collected and centrifuged. Enzyme linked immunosorbent assay (ELISA) was used to determine immunoglobulin G (IgG) antibody titer to the HSV-1 and HSV-2. Results: Totally, HSV-1 and HSV-2 IgG antibody were positive in 285 (79.2%) and 84 (23.3%) subjects, respectively. The seroprevalence of HSV-2 was higher among females (29.0%) compared with males (17.5%) (p Conclusion: Results confirm a high prevalence of HSV infection. Our findings were in agreement with prior studies in which HSV-2 infection was more prevalent among female subjects. The high prevalence of HSV infection underlines the need for focusing on preventive efforts and education among the population.en
DOIhttps://doi.org/en
KeywordSeroprevalenceen
KeywordHerpes simplex virusen
KeywordELISA (enzyme linked immunosorbent assay)en
KeywordIranen
PublisherBrieflandsen
TitleSeroepidemiology of Infection with Herpes Simplex Virus Types 1 and 2 (HSV1 and HSV2) Among Asymptomatic University Students Attending Islamic Azad University of Kazeroun, Southwest of Iranen
TypeResearch Articleen

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