Plasma Selenium Concentration and Glutathione Peroxidase Activity in Breast Cancer Patients Before and After Chemotherapy

Abstract

Background: The chemotherapeutic agents used for treatment of breast cancer are all shown to increase free oxygen radicals and generation of reactive oxygen species. The aim of this study was to evaluate effect of chemotherapy on plasma selenium (Se) concentration and glutathione peroxidase (GPX) activity in breast cancer patients.