Exploring the Link Between Dietary Micronutrient Intake and Helicobacter pylori Positivity: A Case-Control Study
| Author | Mitra Mahmoudi Meymand | en |
| Author | Fatemeh Salajegheh | en |
| Author | Farhad Sarafzadeh | en |
| Author | Mahmoud Reza Heidari | en |
| Author | Fatemeh Dabaghzadeh | en |
| Orcid | Mitra Mahmoudi Meymand [0009-0001-7252-9814] | en |
| Orcid | Fatemeh Dabaghzadeh [0000-0002-5868-9782] | en |
| Issued Date | 2026-11-30 | en |
| Abstract | Background: Helicobacter pylori infection is a major cause of gastric disease, and diet may influence its pathogenicity. Objectives: This study aimed to investigate the association between dietary vitamin and mineral intake and H. pylori infection status. Methods: This case-control study included 90 patients with H. pylori infection (case group) and 90 H. pylori-negative individuals (control group) recruited from the Besat Infectious Diseases Clinic. Daily micronutrient intake was assessed using a 147-item semiquantitative food frequency questionnaire (FFQ). Multivariable logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs), adjusted for age, gender, and body mass index (BMI). Dietary variables included in the final model were selected based on their univariate associations with H. pylori status and biological plausibility. Results: Weight and BMI differed significantly between the case and control groups. Overall, intakes of most dietary vitamins, minerals, macronutrients, and fiber were higher in the control group than in the case group. Multivariable logistic regression showed significant associations between vitamin E, vitamin C, folate, and iron intakes and H. pylori positivity. Conclusions: Lower dietary intake of specific micronutrients was associated with H. pylori positivity. These findings underscore the potential importance of nutritional status; however, randomized controlled trials are needed to determine whether micronutrient supplementation is effective in the prevention or management of H. pylori infection. | en |
| DOI | https://doi.org/10.5812/jjnpp-172796 | en |
| URI | https://brieflands.com/journals/jjnpp/articles/172796 | en |
| Keyword | H. Pylori | en |
| Keyword | Micronutrient Intake | en |
| Keyword | Vitamins | en |
| Keyword | Case-control Study | en |
| Publisher | Brieflands | en |
| Title | Exploring the Link Between Dietary Micronutrient Intake and <i>Helicobacter pylori</i> Positivity: A Case-Control Study | en |
| Type | Research Article | en |
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