Investigation of Intestinal Absorption of Pyridinones in Rat
| Author | Masiholah Taher | en |
| Author | Lotfollah Saghaie | en |
| Author | Maryam Abrahilmi | en |
| Issued Date | 2004-10-31 | en |
| Abstract | Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L1, have been determined. | en |
| DOI | https://doi.org/10.22037/ijpr.2010.602 | en |
| Keyword | Everted gut sac | en |
| Keyword | Partition coefficient | en |
| Keyword | Intestinal absorption | en |
| Keyword | 1.2-dimethyl-3-hydroxypyridin-4-one | en |
| Publisher | Brieflands | en |
| Title | Investigation of Intestinal Absorption of Pyridinones in Rat | en |
| Type | Research Article | en |
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