Association Between Income and Hepatitis B Seroprevalence: A Systematic Review and Meta-analysis
| Author | Ye Ding | en |
| Author | Xueying Sun | en |
| Author | Ying Xu | en |
| Author | Ling Yang | en |
| Author | Yu Zhang | en |
| Author | Qing Shen | en |
| Orcid | Ye Ding [0000-0003-0743-6416] | en |
| Orcid | Qing Shen [0000-0002-3243-5354] | en |
| Issued Date | 2020-10-31 | en |
| Abstract | Context: Hepatitis B serology is very important for both diagnosis and treatment of the diseases. However, evidence regarding the association between income and hepatitis B seroprevalence are not sufficient to make a definitive conclusion. Objectives: This meta-analysis aimed to investigate the association between income inequality and hepatitis B seroprevalence. Methods: We searched PubMed and Web of Science databases to identify all relevant epidemiological studies published up to February 10, 2020. A categorical meta-analysis was applied to pool risk effects of income on hepatitis B seroprevalence. Results: A total of 1525 pieces of literature related to income level and hepatitis B seroprevalence were retrieved, of which 10 articles were finally included. The results revealed a borderline risk (OR: 1.14, 95%CI: 1.00 - 1.30) for hepatitis B seroprevalence (positive for one or more seromarkers) among low-income groups. A significant income effect was observed for HBsAg seroprevalence with a 28% higher risk for low income versus high cases (OR: 1.28, 95%CI: 1.16 - 1.41). However, no statistically significant associations were found between seroprevalence of Anti-HBs, Anti-HBc, and income. Conclusions: This study demonstrated that low income may increase the risk of hepatitis B seroprevalence, especially for HBsAg seroprevalence. Programs on hepatitis B prevention should focus on those with low income. Further studies are warranted to establish causality. | en |
| DOI | https://doi.org/10.5812/hepatmon.104675 | en |
| Keyword | Hepatitis B | en |
| Keyword | Income | en |
| Keyword | Seroprevalence | en |
| Keyword | Meta-analysis | en |
| Publisher | Brieflands | en |
| Title | Association Between Income and Hepatitis B Seroprevalence: A Systematic Review and Meta-analysis | en |
| Type | Systematic Review | en |
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