Prevalence of Hepatitis D Virus Infection and Associated Factors Among HBsAg-Positive Patients in Birjand, Iran, 2012 - 2014
| Author | Gholamreza Sharifzadeh | en |
| Author | Mohammad Hasan Namaei | en |
| Author | Azadeh Ebrahimzadeh | en |
| Author | Zohreh Azarkar | en |
| Author | Mohammad Fereidouni | en |
| Author | Bita Bijari | en |
| Author | Davod Javanmard | en |
| Author | Mehdi Karamian | en |
| Author | Marjan Farzad | en |
| Author | Masood Ziaee | en |
| Orcid | Masood Ziaee [0000-0003-0218-6833] | en |
| Issued Date | 2017-05-31 | en |
| Abstract | Background: It is estimated that about 5% of hepatitis B surface antigen (HBsAg) carriers are infected with hepatitis D virus (HDV) worldwide. Moreover, dual infection with hepatitis B virus (HBV) / HDV causes more severe diseases and leads to a higher risk of mortality. Objectives: This study was performed to determine the prevalence of HDV infection and identify HDV-associated factors among HBsAg-positive patients in Birjand, South Khorasan province, Iran. Methods: This descriptive, cross sectional study was conducted on 5235 participants in line with a previous study on the seroprevalence of HBV in South of Khorasan. HDV was assessed through evaluating the blood serum of diagnosed HBsAg-positive patients (85 cases) by ELISA test. For statistical analysis, descriptive statistics were calculated, using SPSS version 22. Results: In this study, the mean age of HBsAg-positive patients was 45.1 ± 12.9 years (minimum, 22 years; maximum, 70 years). In total, 1 out of 85 cases was positive for HDV virus. The prevalence of HDV infection among HBsAg-positive patients was 1.2% (95% CI, - 1.2 to 3.5). Conclusions: The low prevalence of HDV infection in South of Khorasan was remarkable, considering the great area of this province, use of a comprehensive and inclusive sampling strategy, and mutual borders with Afghanistan. | en |
| DOI | https://doi.org/10.5812/hepatmon.42866 | en |
| Keyword | Hepatitis B | en |
| Keyword | Hepatitis D | en |
| Keyword | Prevalence | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Prevalence of Hepatitis D Virus Infection and Associated Factors Among HBsAg-Positive Patients in Birjand, Iran, 2012 - 2014 | en |
| Type | Research Article | en |
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