TNF Polymorphisms Independently Predict Outcome in Patients with B-Cell Non-Hodgkin’s Lymphoma

AuthorNF Osmanen
AuthorTL Holyoakeen
AuthorA Zeineldinen
AuthorAmal A Elkordyen
AuthorIG McQuakeren
Issued Date2009-03-31en
AbstractObjectives: Tumour Necrosis Factor α (TNFα) and Lymphotoxin α (LTα) have been implicated in the pathogenesis of lymphoproliferative disorders. Patients with B-cell non-Hodgkin’s lymphoma (NHL) often have high serum levels of TNF which may be associated with a poor outcome. TNFα and LTα polymorphisms are known to influence expression of these cytokines and may explain the variable response to therapy.en
DOIhttps://doi.org/en
KeywordB-cell Non-Hodgkin’s lymphomaen
Keywordsurvivalen
KeywordTNF polymorphismsen
PublisherBrieflandsen
TitleTNF Polymorphisms Independently Predict Outcome in Patients with B-Cell Non-Hodgkin’s Lymphomaen
TypeResearch Articleen

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