Single Nucleotide Polymorphisms of DNA Methyltransferase 1 Gene and Gastric Cancer in Iranian Patients: a Case Control Study
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Background: Gastric cancer is one of the most common malignant tumors in Iran. Hypomethylation and/or hypermethylation of DNA have been described in Gastric cancer and is presumed to be an early event in this process. Objective: We hypothesized that Single nucleotide polymorphisms of DNMT1 gene may be associated with the genetic susceptibility to Gastric cancer.