Preparation of Diaminedicarboxyplatinum (II) Functionalized Single-Wall Carbon Nanotube via Bingel Reaction as a Novel Cytotoxic Agent
| Author | Saeed Irannejad | en |
| Author | Mohsen Amini | en |
| Author | Mona Modanlookordi | en |
| Author | Mohammad Shokrzadeh | en |
| Author | Hamid Irannejad | en |
| Issued Date | 2016-10-31 | en |
| Abstract | Carbon nanotubes have unique properties like high stability, high surface to mass ratio and so on which make them suitable for medicinal purpose applications. Treatment of cancer by organoplatinum agents like Cisplatin has become unresponsive in most cases due to low distribution of drug in biological fluids, inability of drug to cross cellular membranes and low stability in biological environments. Recently, carbon nanotubes (CNT) have stimulated much interest to overcome these limitations. Herein, we report the preparation of single-wall carbon nanotube functionalized by diaminedicarboxyplatinum (II) as an analogy of SWCNT-based Carboplatin. | en |
| DOI | https://doi.org/10.22037/ijpr.2016.1917 | en |
| Keyword | Singel-wall carbon nanotube (SWCNT) | en |
| Keyword | Novel anticancer agent | en |
| Keyword | Organoplatinum | en |
| Keyword | Bingel reaction | en |
| Publisher | Brieflands | en |
| Title | Preparation of Diaminedicarboxyplatinum (II) Functionalized Single-Wall Carbon Nanotube via Bingel Reaction as a Novel Cytotoxic Agent | en |
| Type | Original Article | en |
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