Prevalence and Associated Factors of Helicobacter pylori in Dyspeptic Patients at a Shiraz Outpatient Clinic (2022 - 2023)
| Author | Owrang Eilami | en |
| Author | Neda Pouralimohamadi | en |
| Author | Golnaz Yazdanpanah | en |
| Author | Kimiya Kolaei | en |
| Author | Alireza Heiran | en |
| Author | Mehrab Sayadi | en |
| Orcid | Owrang Eilami [0000-0001-6769-9491] | en |
| Orcid | Alireza Heiran [0000-0001-6567-5306] | en |
| Orcid | Mehrab Sayadi [0000-0003-2575-790X] | en |
| Issued Date | 2026-01-31 | en |
| Abstract | Background: Helicobacter pylori infection is a major underlying cause of dyspepsia; however, its regional prevalence and associations with symptoms remain underexplored in southern Iran. Objectives: This study evaluated the prevalence of H. pylori infection and associated factors among patients with dyspepsia using the urea breath test (UBT). Methods: In this cross-sectional study, 145 adults with dyspepsia underwent the carbon-13 urea breath test (13C-UBT) at Motahari Clinic in Shiraz, Iran, during 2022 - 2023. Data on demographic characteristics, symptoms, medication use, and medical history were collected. Results: The overall prevalence of H. pylori infection was 47.6% (95% CI, 39% - 55%). Nausea was independently associated with infection (adjusted odds ratio [aOR] = 2.174; 95% CI, 1.050 - 4.500; P = 0.037), whereas diarrhea approached statistical significance (aOR = 3.154; 95% CI, 0.902 - 11.028; P = 0.072). Occupation was also a significant predictor of infection, with employed participants having 5.979-fold higher odds of positivity (95% CI, 1.267 - 28.22; P = 0.024) than those in the reference occupational category. Conclusions: Nausea and occupational status were independently associated with H. pylori infection. These findings may help identify patients with dyspepsia who could benefit from targeted H. pylori testing; however, larger studies are needed to validate these associations. | en |
| DOI | https://doi.org/10.5812/iji-171982 | en |
| URI | https://brieflands.com/journals/iji/articles/171982 | en |
| Keyword | <i>Helicobacter pylori</i> | en |
| Keyword | Dyspepsia | en |
| Keyword | Urea Breath Test | en |
| Keyword | Nausea | en |
| Keyword | Occupational Exposure | en |
| Publisher | Brieflands | en |
| Title | Prevalence and Associated Factors of <i>Helicobacter pylori</i> in Dyspeptic Patients at a Shiraz Outpatient Clinic (2022 - 2023) | en |
| Type | Research Article | en |
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