In Vitro Antihelmintic Property of Various Seed Oils

Abstract

Seed oils of Passiflora edulis, Jatropa curucas, Tinospora cordifolia, Sesbania grandiflora and Sapindus laurifolia were investigated for their antihelmintic property against Pheritima pasthuma. Three concentrations (10, 50 and 100 mg/ml) of each oil were studied in the bioassay, which involved the determination of time of paralysis and time of death of the worm. Sesbania grandiflora showed the highly significant antihelmintic activity in both the parameters (paralysis and death), while Tinospora cordifolia showed significant effect in case of time of death. Piperazine citrate (10 mg/ml) was included in the assay as standard reference drug.